Sepin-1 is a small compound that inhibits the enzymatic activity of Separase and growth of cancer cells. As part of the IND-enabling studies to develop Sepin-1 as a chemotherapeutic agent, here we have profiled toxicity Sepin-1 in mice Sprague-Dawley in setting good laboratory practice (GLP). The maximum tolerated dose (MTD) of Sepin-1 in mice is 40 mg / kg in a single dose study and 20 mg / kg dose study for 7 days in a row.

Toxicity study consists of two parts-Main Study and Restoration Study. Sepin-1 to 0 (control), 5 (low dose), 10 (median dose), and 20 (high dose) mg / kg given by bolus intravenous injection to mice once a day for 28 consecutive days. The animals were euthanized at the Main Study Day 29, whereas in the study animals were allowed to recover Recovery for 28 days after 28 days Sepin-1 dose before they were euthanized on Day 29 of the off-dose periods.

Although the effects of Sepin-1 in low and median doses were minimal, hematological analysis shows that high doses of Sepin-1 associated with a decrease in red blood cells and hemoglobin, and an increase in the number of reticulocytes and platelets and mean corpuscular volume. Clinical chemistry showed that Sepin-1 causes increases in total bilirubin and a decrease in creatine kinase. histopathological analysis showed Sepin-1 results in minimal bone marrow erythroid hyperplasia, minimal to moderate hematopoiesis extramedullary spleen, minimal depletion of lymphoid spleen, minimal to mild thymic lymphoid depletion, and minimal to rats mild mandibular lymph nodes of lymphoid hyperplasia in men and women on Main Learn.

Those abnormal changes that Sepin-1 depending on the dose and largely reversible after a 28-day recovery period in animals of Recovery Study. Based on our results, we conclude that Sepin-1 at pharmacological dose (5-10 mg / kg) was well-tolerated, with no significant levels of mortality or morbidity, and can be developed as a potential new drug for treating Separase-expressed tumors.

Cohesin cleavage by separase enhanced with different substrate 

Chromosome segregation began when a cysteine ​​protease, separase, splitting Scc1 transition subunit of cohesin at the metaphase-to-anaphase. Separase inhibited before metaphase with securin tightly bound protein, which contains motifs separase pseudosubstrate blocking the active site.

To investigate the substrate specificity and regulation separase, here we developed a system to produce recombinant human separase securin free. Using these enzymes, we identified motif Scc1 LPE on a substrate different from the cleavage site and necessary for the rapid and specific cleavage of the substrate. LPE Securin also contain conserved motifs, and we provide evidence that this sequence motif involvement Scc1 separase block LPE. Our results indicate that rapid cohesin cleavage by separase require interaction substrate docking outside the active site. This interaction is blocked by securin, providing a second mechanism which inhibits securin cohesin cleavage.

eat-dose pharmacokinetic study Sepin-1 in mice. Sepin-1 intravenously to mice Sprague-Dawley once a day for 28 days in three different (5, 10 and 20mg / kg) dose. Blood samples were taken after dosing on days 1 and 28. Sepin-1 is not stable in phosphate-buffered saline at the base and stable pH buffer such as citric acid-buffered saline (pH 4.0). UHPLC-MS analysis showed Sepin-1 rapidly metabolized in vivo.

(-)-MK 801
B1627-10	ApexBio	10 mg	EUR 122.4
Description: (+)-MK 801 Maleate is a potent antagonist of NMDA with Ki value of 30.5nM [1].MK 801 is a potent anticonvulsant exhibits both anxiolytic and sympathomimetic properties. It is found to be a noncompetitive antagonist of NMDA. MK 801 can penetrate into the central nervous system.

(-)-MK 801
B1627-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 135.6
Description: (+)-MK 801 Maleate is a potent antagonist of NMDA with Ki value of 30.5nM [1].MK 801 is a potent anticonvulsant exhibits both anxiolytic and sympathomimetic properties. It is found to be a noncompetitive antagonist of NMDA. MK 801 can penetrate into the central nervous system.

(-)-MK 801
B1627-50	ApexBio	50 mg	EUR 268.8
Description: (+)-MK 801 Maleate is a potent antagonist of NMDA with Ki value of 30.5nM [1].MK 801 is a potent anticonvulsant exhibits both anxiolytic and sympathomimetic properties. It is found to be a noncompetitive antagonist of NMDA. MK 801 can penetrate into the central nervous system.

JTC-801
HY-13274	MedChemExpress	50mg	EUR 472.8

Goat polyclonal antibody for Cytomegalovirus
801	Virostat	1 ml	EUR 327.53
Description: This is goat polyclonal antibody against Cytomegalovirus AD 169 for WB, ELISA.

(+)-MK 801 Maleate
A8896-10	ApexBio	10 mg	EUR 126
Description: (+)-MK 801 is a potent antagonist of NMDA with Ki value of 30.5nM [1].MK 801 is a potent anticonvulsant exhibits both anxiolytic and sympathomimetic properties.

(+)-MK 801 Maleate
A8896-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 135.6
Description: (+)-MK 801 is a potent antagonist of NMDA with Ki value of 30.5nM [1].MK 801 is a potent anticonvulsant exhibits both anxiolytic and sympathomimetic properties.

(+)-MK 801 Maleate
A8896-50	ApexBio	50 mg	EUR 319.2
Description: (+)-MK 801 is a potent antagonist of NMDA with Ki value of 30.5nM [1].MK 801 is a potent anticonvulsant exhibits both anxiolytic and sympathomimetic properties.

(+)-MK 801 Hydrogen Maleate
B2326-25	Biovision	each	EUR 418.8

(+)-MK 801 Hydrogen Maleate
B2326-5	Biovision	each	EUR 157.2

(-)-MK 801 Hydrogen Maleate
B2327-25	Biovision	each	EUR 418.8

(-)-MK 801 Hydrogen Maleate
B2327-5	Biovision	each	EUR 157.2

Dermatopontin Recombinant Protein
91-801	ProSci	0.05 mg	EUR 588.3
Description: Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT, is a secreted protein which belongs to the dermatopontin family. DPT is expressed in various tissues, such as fibroblasts, heart, skeletal muscle, brain and pancreas. It seems to mediate adhesion by cell surface integrin binding. DPT may serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. DPT can enhance TGFB1 activity through interaction with decorin. In addition, DPT accelerates collagen fibril formation, stabilizes collagen fibrils against low-temperature dissociation and inhibits cell proliferation.

Cellufine MAX DexS-Vir
21-801	JNC America	50 ml	EUR 580.8

pSMPUW-GFP-LC3 Lentiviral Expression Vector
LTV-801	Cell Biolabs	10 µg	EUR 1444.8
Description: Expression vector contains a fusion of GFP and LC3. A separate GFP control vector is also included.

pMXs-GFP-LC3 Retroviral Vector
RTV-801	Cell Biolabs	10 ?g	EUR 1402.8
Description: Expression vector contains a fusion of GFP and LC3. A separate GFP control vector is also included.

OxiSelect In Vitro Nitric Oxide (Nitrite / Nitrate) Assay Kit (Fluorometric)
STA-801	Cell Biolabs	100 assays	EUR 567.6
Description: Cell Biolabs? OxiSelect Nitric Oxide (Nitrite/Nitrate) Assay Kit is a simple, colorimetric assay that quantitatively measures NO in various samples by NO2-/NO3- determination.  First, the nitrate (NO3-) in the sample is converted to nitrite (NO2-) by nitrate reductase enzyme.  Next, total nitrite is detected with Griess Reagents as a colored azo dye product (absorbance 540 nm).  Each kit provides sufficient reagents to perform up to 100 assays using a 96-well microtiter plate format, including blanks, standards and unknown samples.  The kit is suitable for serum, plasma, urine, saliva, lysates, and media (see Preparation of Samples) with detection sensitivity limit of ~ 2 µM (in 50 µL sample volume).

Tris EDTA Saline, 10mM Tris HCl , 1mM EDTA, 2M Nacl
T8150-801	GenDepot	8L	EUR 144

Recombinant (E.Coli) Human Myoglobin
RP-801	Alpha Diagnostics	500 ug	EUR 489.6

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCA0801-250	Biotium	250uL	EUR 459.6
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), APC conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCAP0801-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCAP0801-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC610801-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF660R conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC610801-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF660R conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNUM0801-50	Biotium	50uL	EUR 474
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), 1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCR0801-250	Biotium	250uL	EUR 459.6
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), RPE conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNUB0801-100	Biotium	100uL	EUR 250.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Concentration: 0.2mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNUB0801-500	Biotium	500uL	EUR 549.6
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Concentration: 0.2mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC430801-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF543 conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC430801-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF543 conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC400801-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF640R conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC400801-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF640R conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC880801-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF488A conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC880801-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF488A conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC800801-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF680 conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC800801-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF680 conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC810801-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF680R conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC810801-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF680R conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCH0801-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCH0801-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCP0801-250	Biotium	250uL	EUR 459.6
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), PerCP conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC050801-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF405M conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC050801-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF405M conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC680801-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF568 conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC680801-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF568 conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC700801-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF770 conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC700801-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF770 conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCB0801-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Biotin conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCB0801-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Biotin conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC940801-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF594 conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC940801-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF594 conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC550801-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF555 conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC550801-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF555 conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC470801-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF647 conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC470801-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF647 conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC040801-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF405S conjugate, Concentration: 0.1mg/mL

PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC040801-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF405S conjugate, Concentration: 0.1mg/mL

96 WELL WHITE LOW PROFILE PCR MICROPLATE FOR AB
PCR-96-LP-AB-W	CORNING	25/pk	EUR 465.6
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

Prostate Specific Antigen (PSA); Clone KLK3/801 (Concentrate)
RA0009-C.1	ScyTek Laboratories	0.1 ml	EUR 150

Prostate Specific Antigen (PSA); Clone KLK3/801 (Concentrate)
RA0009-C.5	ScyTek Laboratories	0.5 ml	EUR 360

Recombinant Streptococcus Pyogenes ftsK Protein (aa 1-801)
VAng-Cr8109-inquire	Creative Biolabs	inquire	Ask for price
Description: Streptococcus Pyogenes serotype M18 DNA translocase FtsK (ftsK), recombinant protein.

Recombinant Neisseria Gonorrhoeae lptD Protein (aa 1-801)
VAng-Wyb2182-inquire	Creative Biolabs	inquire	Ask for price
Description: Neisseria Gonorrhoeae (strain ATCC 700825 / FA 1090) LPS-assembly protein lptD, recombinant protein.

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC941256-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF594 conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC941256-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF594 conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCA1256-250	Biotium	250uL	EUR 459.6
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), APC conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCAP1256-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCAP1256-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC611256-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF660R conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC611256-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF660R conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNUM1256-50	Biotium	50uL	EUR 474
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), 1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCP1256-250	Biotium	250uL	EUR 459.6
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), PerCP conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCR1256-250	Biotium	250uL	EUR 459.6
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), RPE conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNUB1256-100	Biotium	100uL	EUR 250.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Concentration: 0.2mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNUB1256-500	Biotium	500uL	EUR 549.6
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Concentration: 0.2mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC431256-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF543 conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC431256-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF543 conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC051256-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF405M conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC051256-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF405M conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC401256-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF640R conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC401256-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF640R conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC811256-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF680R conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC811256-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF680R conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC881256-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF488A conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC881256-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF488A conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC801256-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF680 conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC801256-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF680 conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCH1256-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCH1256-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC041256-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF405S conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC041256-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF405S conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC681256-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF568 conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC681256-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF568 conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC701256-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF770 conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC701256-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF770 conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC551256-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF555 conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC551256-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF555 conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCB1256-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Biotin conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCB1256-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Biotin conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC471256-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF647 conjugate, Concentration: 0.1mg/mL

Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC471256-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF647 conjugate, Concentration: 0.1mg/mL

Soyasaponin Ab
HY-N3026	MedChemExpress	5mg	EUR 338.4

AB-423
HY-112142	MedChemExpress	100mg	EUR 2469.6

AB-680
HY-125286	MedChemExpress	10mg	EUR 2126.4

AB-MECA
HY-19365	MedChemExpress	5mg	EUR 456

Activin AB
PR15011	Neuromics	5 ug	EUR 577.2

Anti-Prostate Specific Antigen Antibody Clone KLK3/801, Unconjugated-100ug
354-MSM2-P1	EnQuireBio	100ug	EUR 513.6

Anti-CD22 (Moxetumomab pasudotox)-SPDB-DM4 ADC
ADC-W-801	Creative Biolabs	1mg	Ask for price
Description: This ADC product is comprised of an anti-CD22 monoclonal antibody conjugated via a SPDB linker to DM4

Human Anti-Meningococcal Group A Oligosaccharides IgG negative control serum
600-801-ANC	Alpha Diagnostics	1 ml	EUR 196.8

Human Anti-Meningococcal Group A Oligosaccharides IgG positive control serum
600-801-APC	Alpha Diagnostics	1 ml	EUR 270

Small intestine Tissue Slide (Normal)
11-801-10um	ProSci	10 um	EUR 241.8

Small intestine Tissue Slide (Normal)
11-801-4um	ProSci	4 um	EUR 216.6

Mouse IgG2b Isotype Control Purified
11-801-C025	ExBio	0.025 mg	EUR 105.6

Mouse IgG2b Isotype Control Purified
11-801-C100	ExBio	0.1 mg	EUR 163.2

Stomach Tissue Slide (Normal)
10-801-10um	ProSci	10 um	EUR 241.8

Stomach Tissue Slide (Normal)
10-801-4um	ProSci	4 um	EUR 216.6

Melanoma Tissue Slide (Skin- Melanoma)
12-801-10um	ProSci	10 um	EUR 241.8

Melanoma Tissue Slide (Skin- Melanoma)
12-801-4um	ProSci	4 um	EUR 216.6

OxiSelect In Vitro Nitric Oxide (Nitrite / Nitrate) Assay Kit (Fluorometric)
STA-801-5	Cell Biolabs	5 x 100 assays	EUR 2182.8
Description: Cell Biolabs? OxiSelect Nitric Oxide (Nitrite/Nitrate) Assay Kit is a simple, colorimetric assay that quantitatively measures NO in various samples by NO2-/NO3- determination.  First, the nitrate (NO3-) in the sample is converted to nitrite (NO2-) by nitrate reductase enzyme.  Next, total nitrite is detected with Griess Reagents as a colored azo dye product (absorbance 540 nm).  Each kit provides sufficient reagents to perform up to 100 assays using a 96-well microtiter plate format, including blanks, standards and unknown samples.  The kit is suitable for serum, plasma, urine, saliva, lysates, and media (see Preparation of Samples) with detection sensitivity limit of ~ 2 µM (in 50 µL sample volume).

Mouse ACV-AB(Activin AB) ELISA Kit
EM0312	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml

PDGF-AB/ Rat PDGF- AB ELISA Kit
ELA-E0112r	Lifescience Market	96 Tests	EUR 1063.2

MBP-Ab/ Rat MBP- Ab ELISA Kit
ELA-E0170r	Lifescience Market	96 Tests	EUR 1063.2

MC Ab/ Rat MC Ab ELISA Kit
ELA-E0390r	Lifescience Market	96 Tests	EUR 1063.2

TPO-Ab/ Rat TPO- Ab ELISA Kit
ELA-E0442r	Lifescience Market	96 Tests	EUR 1063.2

Thyroid Ab/ Rat Thyroid Ab ELISA Kit
ELA-E0844r	Lifescience Market	96 Tests	EUR 1063.2

GNRHR-Ab/ Rat GNRHR- Ab ELISA Kit
ELA-E0962r	Lifescience Market	96 Tests	EUR 1063.2

MAG Ab/ Rat MAG Ab ELISA Kit
ELA-E0995r	Lifescience Market	96 Tests	EUR 1063.2

DNP-Ab/ Rat DNP- Ab ELISA Kit
ELA-E1122r	Lifescience Market	96 Tests	EUR 1063.2

ENA-Ab/ Rat ENA- Ab ELISA Kit
ELA-E1124r	Lifescience Market	96 Tests	EUR 1063.2

RNP-Ab/ Rat RNP- Ab ELISA Kit
ELA-E1129r	Lifescience Market	96 Tests	EUR 1063.2

rHu PDGF-AB
AK8282-0002	Akron Biotech	2µg	Ask for price

rHu PDGF-AB
AK8282-0010	Akron Biotech	10µg	Ask for price

rHu PDGF-AB
AK8282-0100	Akron Biotech	100µg	Ask for price

rHu PDGF-AB
AK8282-1000	Akron Biotech	1mg	Ask for price

PDGF AB protein
30R-2610	Fitzgerald	10 ug	EUR 430.8
Description: Purified recombinant Human PDGF AB protein

AB-2950 MPEC
351201	Atto	5unit	EUR 334.8
Description: Super oxide(O2) reaction system L ight Emittingreagent

AB-2960 BactoLumix
3512020	Atto	2unit	EUR 378
Description: Menadione oxidation-reduction reaction system for probiotic measurement

AB-3000B Cellgraph
3600000	Atto	unit	EUR 120

PDGF AB protein
30R-AP003	Fitzgerald	10 ug	EUR 327.6
Description: Purified recombinant Human PDGF AB protein

NGAL (Capture Ab)
20-abx019240	Abbexa	EUR 176.40 EUR 777.60 EUR 260.40 EUR 493.20 EUR 126.00	100 ug 1 mg 200 ug 500 ug 50 ug

NGAL (Capture Ab)
20-abx019241	Abbexa	EUR 176.40 EUR 777.60 EUR 493.20	100 ug 1 mg 500 ug

NGAL (Detection Ab)
abx019242-100ug	Abbexa	100 ug	EUR 777.6

Apoa5 (ab) Antibody
abx010415-100ul	Abbexa	100 ul	EUR 493.2

AB-Pinaca Antibody
abx023942-1mg	Abbexa	1 mg	EUR 744

AB-Pinaca Antibody
abx023943-1mg	Abbexa	1 mg	EUR 744

Apoa5 (ab) Antibody
BF0615	Affbiotech	200ul	EUR 540

Ab Rabbit GluR2*
P40014-100uL	Pel-Freez	100uL	Ask for price

Ab Rabbit MARCKS*
P40017-100uL	Pel-Freez	100uL	Ask for price

Ab MS GluR1*
P80000-100uL	Pel-Freez	100uL	Ask for price

Activin AB, CF
PR15011CF	Neuromics	5 ug	EUR 577.2

PDGF - AB Human
PR27062	Neuromics	2 ug	EUR 229.2

Human Serum AB
SC00B14	Neuromics	100 ml	EUR 434.4

Ab buffer kit
28903059	Scientific Laboratory Supplies	EACH	EUR 159.6

Elk-1 Ab
3387-100	Biovision	each	EUR 405.6

ELISA kit for Mouse ACV-AB (Activin AB)  Kit
E-EL-M2660	Elabscience Biotech	1 plate of 96 wells	EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Mouse ACV-AB (Activin AB)  Kit in samples from Serum, Plasma, Cell supernatant

ACV-AB ELISA Kit| Mouse Activin AB ELISA Kit
EF012990	Lifescience Market	96 Tests	EUR 826.8

IFN-Gamma ab/ Rat IFN- Gamma ab ELISA Kit
ELA-E1716r	Lifescience Market	96 Tests	EUR 1063.2

G-CSF ab/ Rat G- CSF ab ELISA Kit
ELA-E1717r	Lifescience Market	96 Tests	EUR 1063.2

n-DNA-Ab/ Rat n- DNA- Ab ELISA Kit
ELA-E1126r	Lifescience Market	96 Tests	EUR 1063.2

Sc1-70-Ab/ Rat Sc1- 70- Ab ELISA Kit
ELA-E1131r	Lifescience Market	96 Tests	EUR 1063.2

Mouse monoclonal Anti-HA-tag peptide IgG
AB-10110	Alpha Diagnostics	100 ug	EUR 562.8

Mouse Monoclonal Anti-Human Interleukin-2 IgG
AB-10210	Alpha Diagnostics	100 ug	EUR 416.4

Rat Monoclonal Anti-Mouse Interleukin-2 receptor IgG
AB-10310	Alpha Diagnostics	100 ug	EUR 416.4

Mouse Monoclonal Anti-Human Interleukin-2 receptor IgG
AB-10410	Alpha Diagnostics	100 ug	EUR 416.4

Rat Monoclonal Anti-Mouse Interleukin-2 IgG
AB-10510	Alpha Diagnostics	100 ug	EUR 416.4

Mouse Monoclonal Anti-Human Interleukin-3 IgG
AB-10610	Alpha Diagnostics	100 ug	EUR 416.4

Mouse Monoclonal Anti-Human Interleukin-4 IgG
AB-10710	Alpha Diagnostics	100 ug	EUR 416.4

Rat Monoclonal Anti-Mouse Interleukin-4 IgG
AB-10810	Alpha Diagnostics	100 ug	EUR 416.4

Mouse Monoclonal Anti-Human Interleukin-6 IgG
AB-10910	Alpha Diagnostics	100 ug	EUR 416.4

Mouse Monoclonal Anti-Human Interleukin-7 IgG
AB-11010	Alpha Diagnostics	100 ug	EUR 416.4

Mouse Monoclonal Anti-Human Interleukin-8 IgG
AB-11110	Alpha Diagnostics	100 ug	EUR 416.4

Mouse Monoclonal Anti-Human Interleukin-10 IgG
AB-11210	Alpha Diagnostics	100 ug	EUR 416.4

One of the major metabolite is stirring the amine of 2,2-dimethyl-5-nitro-2H-benzimidazole (named Sepin-1.55). Sepin-concentration in the blood samples was 1.55 Sepin-1 depending on the dose and used for pharmacokinetic analysis Sepin-1. Tmax was about 5-15 minutes.