Separase activity distribution can be a marker of major molecular response and proliferation of CD34+ cells in TKI-treated chronic myeloid leukemia patients.
Sepin-1 is a small compound that inhibits the enzymatic activity of Separase and growth of cancer cells. As part of the IND-enabling studies to develop Sepin-1 as a chemotherapeutic agent, here we have profiled toxicity Sepin-1 in mice Sprague-Dawley in setting good laboratory practice (GLP). The maximum tolerated dose (MTD) of Sepin-1 in mice is 40 mg / kg in a single dose study and 20 mg / kg dose study for 7 days in a row.
Toxicity study consists of two parts-Main Study and Restoration Study. Sepin-1 to 0 (control), 5 (low dose), 10 (median dose), and 20 (high dose) mg / kg given by bolus intravenous injection to mice once a day for 28 consecutive days. The animals were euthanized at the Main Study Day 29, whereas in the study animals were allowed to recover Recovery for 28 days after 28 days Sepin-1 dose before they were euthanized on Day 29 of the off-dose periods.
Although the effects of Sepin-1 in low and median doses were minimal, hematological analysis shows that high doses of Sepin-1 associated with a decrease in red blood cells and hemoglobin, and an increase in the number of reticulocytes and platelets and mean corpuscular volume. Clinical chemistry showed that Sepin-1 causes increases in total bilirubin and a decrease in creatine kinase. histopathological analysis showed Sepin-1 results in minimal bone marrow erythroid hyperplasia, minimal to moderate hematopoiesis extramedullary spleen, minimal depletion of lymphoid spleen, minimal to mild thymic lymphoid depletion, and minimal to rats mild mandibular lymph nodes of lymphoid hyperplasia in men and women on Main Learn.
Those abnormal changes that Sepin-1 depending on the dose and largely reversible after a 28-day recovery period in animals of Recovery Study. Based on our results, we conclude that Sepin-1 at pharmacological dose (5-10 mg / kg) was well-tolerated, with no significant levels of mortality or morbidity, and can be developed as a potential new drug for treating Separase-expressed tumors.
Toxicity study of separase inhibitor-Sepin-1 in Sprague-Dawley rats.
Cohesin cleavage by separase enhanced with different substrate
Chromosome segregation began when a cysteine protease, separase, splitting Scc1 transition subunit of cohesin at the metaphase-to-anaphase. Separase inhibited before metaphase with securin tightly bound protein, which contains motifs separase pseudosubstrate blocking the active site.
To investigate the substrate specificity and regulation separase, here we developed a system to produce recombinant human separase securin free. Using these enzymes, we identified motif Scc1 LPE on a substrate different from the cleavage site and necessary for the rapid and specific cleavage of the substrate. LPE Securin also contain conserved motifs, and we provide evidence that this sequence motif involvement Scc1 separase block LPE. Our results indicate that rapid cohesin cleavage by separase require interaction substrate docking outside the active site. This interaction is blocked by securin, providing a second mechanism which inhibits securin cohesin cleavage.
eat-dose pharmacokinetic study Sepin-1 in mice. Sepin-1 intravenously to mice Sprague-Dawley once a day for 28 days in three different (5, 10 and 20mg / kg) dose. Blood samples were taken after dosing on days 1 and 28. Sepin-1 is not stable in phosphate-buffered saline at the base and stable pH buffer such as citric acid-buffered saline (pH 4.0). UHPLC-MS analysis showed Sepin-1 rapidly metabolized in vivo.
(-)-MK 801
B1627-10
ApexBio
10 mg
EUR 122.4
Description: (+)-MK 801 Maleate is a potent antagonist of NMDA with Ki value of 30.5nM [1].MK 801 is a potent anticonvulsant exhibits both anxiolytic and sympathomimetic properties. It is found to be a noncompetitive antagonist of NMDA. MK 801 can penetrate into the central nervous system.
(-)-MK 801
B1627-5.1
ApexBio
10 mM (in 1mL DMSO)
EUR 135.6
Description: (+)-MK 801 Maleate is a potent antagonist of NMDA with Ki value of 30.5nM [1].MK 801 is a potent anticonvulsant exhibits both anxiolytic and sympathomimetic properties. It is found to be a noncompetitive antagonist of NMDA. MK 801 can penetrate into the central nervous system.
(-)-MK 801
B1627-50
ApexBio
50 mg
EUR 268.8
Description: (+)-MK 801 Maleate is a potent antagonist of NMDA with Ki value of 30.5nM [1].MK 801 is a potent anticonvulsant exhibits both anxiolytic and sympathomimetic properties. It is found to be a noncompetitive antagonist of NMDA. MK 801 can penetrate into the central nervous system.
Goat polyclonal antibody for Cytomegalovirus
801
Virostat
1 ml
EUR 327.53
Description: This is goat polyclonal antibody against Cytomegalovirus AD 169 for WB, ELISA.
(+)-MK 801 Maleate
A8896-10
ApexBio
10 mg
EUR 126
Description: (+)-MK 801 is a potent antagonist of NMDA with Ki value of 30.5nM [1].MK 801 is a potent anticonvulsant exhibits both anxiolytic and sympathomimetic properties.
(+)-MK 801 Maleate
A8896-5.1
ApexBio
10 mM (in 1mL DMSO)
EUR 135.6
Description: (+)-MK 801 is a potent antagonist of NMDA with Ki value of 30.5nM [1].MK 801 is a potent anticonvulsant exhibits both anxiolytic and sympathomimetic properties.
(+)-MK 801 Maleate
A8896-50
ApexBio
50 mg
EUR 319.2
Description: (+)-MK 801 is a potent antagonist of NMDA with Ki value of 30.5nM [1].MK 801 is a potent anticonvulsant exhibits both anxiolytic and sympathomimetic properties.
(+)-MK 801 Hydrogen Maleate
B2326-25
Biovision
each
EUR 418.8
(+)-MK 801 Hydrogen Maleate
B2326-5
Biovision
each
EUR 157.2
(-)-MK 801 Hydrogen Maleate
B2327-25
Biovision
each
EUR 418.8
(-)-MK 801 Hydrogen Maleate
B2327-5
Biovision
each
EUR 157.2
Dermatopontin Recombinant Protein
91-801
ProSci
0.05 mg
EUR 588.3
Description: Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT, is a secreted protein which belongs to the dermatopontin family. DPT is expressed in various tissues, such as fibroblasts, heart, skeletal muscle, brain and pancreas. It seems to mediate adhesion by cell surface integrin binding. DPT may serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. DPT can enhance TGFB1 activity through interaction with decorin. In addition, DPT accelerates collagen fibril formation, stabilizes collagen fibrils against low-temperature dissociation and inhibits cell proliferation.
Cellufine MAX DexS-Vir
21-801
JNC America
50 ml
EUR 580.8
pSMPUW-GFP-LC3 Lentiviral Expression Vector
LTV-801
Cell Biolabs
10 µg
EUR 1444.8
Description: Expression vector contains a fusion of GFP and LC3. A separate GFP control vector is also included.
pMXs-GFP-LC3 Retroviral Vector
RTV-801
Cell Biolabs
10 ?g
EUR 1402.8
Description: Expression vector contains a fusion of GFP and LC3. A separate GFP control vector is also included.
OxiSelect In Vitro Nitric Oxide (Nitrite / Nitrate) Assay Kit (Fluorometric)
STA-801
Cell Biolabs
100 assays
EUR 567.6
Description: Cell Biolabs? OxiSelect Nitric Oxide (Nitrite/Nitrate) Assay Kit is a simple, colorimetric assay that quantitatively measures NO in various samples by NO2-/NO3- determination. First, the nitrate (NO3-) in the sample is converted to nitrite (NO2-) by nitrate reductase enzyme. Next, total nitrite is detected with Griess Reagents as a colored azo dye product (absorbance 540 nm). Each kit provides sufficient reagents to perform up to 100 assays using a 96-well microtiter plate format, including blanks, standards and unknown samples. The kit is suitable for serum, plasma, urine, saliva, lysates, and media (see Preparation of Samples) with detection sensitivity limit of ~ 2 µM (in 50 µL sample volume).
Tris EDTA Saline, 10mM Tris HCl , 1mM EDTA, 2M Nacl
T8150-801
GenDepot
8L
EUR 144
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCA0801-250
Biotium
250uL
EUR 459.6
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), APC conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCAP0801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCAP0801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC610801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF660R conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC610801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF660R conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNUM0801-50
Biotium
50uL
EUR 474
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), 1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCR0801-250
Biotium
250uL
EUR 459.6
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), RPE conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNUB0801-100
Biotium
100uL
EUR 250.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Concentration: 0.2mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNUB0801-500
Biotium
500uL
EUR 549.6
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Concentration: 0.2mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC430801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF543 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC430801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF543 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC400801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF640R conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC400801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF640R conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC880801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF488A conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC880801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF488A conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC800801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF680 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC800801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF680 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC810801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF680R conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC810801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF680R conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCH0801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCH0801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCP0801-250
Biotium
250uL
EUR 459.6
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), PerCP conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC050801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF405M conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC050801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF405M conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC680801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF568 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC680801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF568 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC700801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF770 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC700801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF770 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCB0801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Biotin conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCB0801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Biotin conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC940801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF594 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC940801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF594 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC550801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF555 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC550801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF555 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC470801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF647 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC470801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF647 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC040801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF405S conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC040801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF405S conjugate, Concentration: 0.1mg/mL
96 WELL WHITE LOW PROFILE PCR MICROPLATE FOR AB
PCR-96-LP-AB-W
CORNING
25/pk
EUR 465.6
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen
Prostate Specific Antigen (PSA); Clone KLK3/801 (Concentrate)
RA0009-C.1
ScyTek Laboratories
0.1 ml
EUR 150
Prostate Specific Antigen (PSA); Clone KLK3/801 (Concentrate)
RA0009-C.5
ScyTek Laboratories
0.5 ml
EUR 360
Recombinant Streptococcus Pyogenes ftsK Protein (aa 1-801)
VAng-Cr8109-inquire
Creative Biolabs
inquire
Ask for price
Description: Streptococcus Pyogenes serotype M18 DNA translocase FtsK (ftsK), recombinant protein.
Recombinant Neisseria Gonorrhoeae lptD Protein (aa 1-801)
VAng-Wyb2182-inquire
Creative Biolabs
inquire
Ask for price
Description: Neisseria Gonorrhoeae (strain ATCC 700825 / FA 1090) LPS-assembly protein lptD, recombinant protein.
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC941256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF594 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC941256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF594 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCA1256-250
Biotium
250uL
EUR 459.6
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), APC conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCAP1256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCAP1256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC611256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF660R conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC611256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF660R conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNUM1256-50
Biotium
50uL
EUR 474
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), 1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCP1256-250
Biotium
250uL
EUR 459.6
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), PerCP conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCR1256-250
Biotium
250uL
EUR 459.6
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), RPE conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNUB1256-100
Biotium
100uL
EUR 250.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Concentration: 0.2mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNUB1256-500
Biotium
500uL
EUR 549.6
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Concentration: 0.2mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC431256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF543 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC431256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF543 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC051256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF405M conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC051256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF405M conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC401256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF640R conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC401256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF640R conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC811256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF680R conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC811256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF680R conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC881256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF488A conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC881256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF488A conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC801256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF680 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC801256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF680 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCH1256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCH1256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC041256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF405S conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC041256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF405S conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC681256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF568 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC681256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF568 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC701256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF770 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC701256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF770 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC551256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF555 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC551256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF555 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCB1256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Biotin conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCB1256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Biotin conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC471256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF647 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC471256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF647 conjugate, Concentration: 0.1mg/mL
Anti-Prostate Specific Antigen Antibody Clone KLK3/801, Unconjugated-100ug
354-MSM2-P1
EnQuireBio
100ug
EUR 513.6
Anti-CD22 (Moxetumomab pasudotox)-SPDB-DM4 ADC
ADC-W-801
Creative Biolabs
1mg
Ask for price
Description: This ADC product is comprised of an anti-CD22 monoclonal antibody conjugated via a SPDB linker to DM4
Human Anti-Meningococcal Group A Oligosaccharides IgG negative control serum
600-801-ANC
Alpha Diagnostics
1 ml
EUR 196.8
Human Anti-Meningococcal Group A Oligosaccharides IgG positive control serum
600-801-APC
Alpha Diagnostics
1 ml
EUR 270
Small intestine Tissue Slide (Normal)
11-801-10um
ProSci
10 um
EUR 241.8
Small intestine Tissue Slide (Normal)
11-801-4um
ProSci
4 um
EUR 216.6
Mouse IgG2b Isotype Control Purified
11-801-C025
ExBio
0.025 mg
EUR 105.6
Mouse IgG2b Isotype Control Purified
11-801-C100
ExBio
0.1 mg
EUR 163.2
Stomach Tissue Slide (Normal)
10-801-10um
ProSci
10 um
EUR 241.8
Stomach Tissue Slide (Normal)
10-801-4um
ProSci
4 um
EUR 216.6
Melanoma Tissue Slide (Skin- Melanoma)
12-801-10um
ProSci
10 um
EUR 241.8
Melanoma Tissue Slide (Skin- Melanoma)
12-801-4um
ProSci
4 um
EUR 216.6
OxiSelect In Vitro Nitric Oxide (Nitrite / Nitrate) Assay Kit (Fluorometric)
STA-801-5
Cell Biolabs
5 x 100 assays
EUR 2182.8
Description: Cell Biolabs? OxiSelect Nitric Oxide (Nitrite/Nitrate) Assay Kit is a simple, colorimetric assay that quantitatively measures NO in various samples by NO2-/NO3- determination. First, the nitrate (NO3-) in the sample is converted to nitrite (NO2-) by nitrate reductase enzyme. Next, total nitrite is detected with Griess Reagents as a colored azo dye product (absorbance 540 nm). Each kit provides sufficient reagents to perform up to 100 assays using a 96-well microtiter plate format, including blanks, standards and unknown samples. The kit is suitable for serum, plasma, urine, saliva, lysates, and media (see Preparation of Samples) with detection sensitivity limit of ~ 2 µM (in 50 µL sample volume).
Mouse ACV-AB(Activin AB) ELISA Kit
EM0312
FN Test
96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml
PDGF AB protein
30R-2610
Fitzgerald
10 ug
EUR 430.8
Description: Purified recombinant Human PDGF AB protein
AB-2950 MPEC
351201
Atto
5unit
EUR 334.8
Description: Super oxide(O2) reaction system L ight Emittingreagent
AB-2960 BactoLumix
3512020
Atto
2unit
EUR 378
Description: Menadione oxidation-reduction reaction system for probiotic measurement
AB-3000B Cellgraph
3600000
Atto
unit
EUR 120
PDGF AB protein
30R-AP003
Fitzgerald
10 ug
EUR 327.6
Description: Purified recombinant Human PDGF AB protein
NGAL (Capture Ab)
20-abx019240
Abbexa
EUR 176.40
EUR 777.60
EUR 260.40
EUR 493.20
EUR 126.00
100 ug
1 mg
200 ug
500 ug
50 ug
NGAL (Capture Ab)
20-abx019241
Abbexa
EUR 176.40
EUR 777.60
EUR 493.20
NGAL (Detection Ab)
abx019242-100ug
Abbexa
100 ug
EUR 777.6
Apoa5 (ab) Antibody
abx010415-100ul
Abbexa
100 ul
EUR 493.2
AB-Pinaca Antibody
abx023942-1mg
Abbexa
1 mg
EUR 744
AB-Pinaca Antibody
abx023943-1mg
Abbexa
1 mg
EUR 744
Apoa5 (ab) Antibody
BF0615
Affbiotech
200ul
EUR 540
Ab Rabbit GluR2*
P40014-100uL
Pel-Freez
100uL
Ask for price
Ab Rabbit MARCKS*
P40017-100uL
Pel-Freez
100uL
Ask for price
Ab MS GluR1*
P80000-100uL
Pel-Freez
100uL
Ask for price
Activin AB, CF
PR15011CF
Neuromics
5 ug
EUR 577.2
PDGF - AB Human
PR27062
Neuromics
2 ug
EUR 229.2
Human Serum AB
SC00B14
Neuromics
100 ml
EUR 434.4
ELISA kit for Mouse ACV-AB (Activin AB) Kit
E-EL-M2660
Elabscience Biotech
1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Mouse ACV-AB (Activin AB) Kit in samples from Serum, Plasma, Cell supernatant
ACV-AB ELISA Kit| Mouse Activin AB ELISA Kit
EF012990
Lifescience Market
96 Tests
EUR 826.8
IFN-Gamma ab/ Rat IFN- Gamma ab ELISA Kit
ELA-E1716r
Lifescience Market
96 Tests
EUR 1063.2
Mouse Monoclonal Anti-Human Interleukin-2 IgG
AB-10210
Alpha Diagnostics
100 ug
EUR 416.4
Rat Monoclonal Anti-Mouse Interleukin-2 receptor IgG
AB-10310
Alpha Diagnostics
100 ug
EUR 416.4
Mouse Monoclonal Anti-Human Interleukin-2 receptor IgG
AB-10410
Alpha Diagnostics
100 ug
EUR 416.4
Rat Monoclonal Anti-Mouse Interleukin-2 IgG
AB-10510
Alpha Diagnostics
100 ug
EUR 416.4
Mouse Monoclonal Anti-Human Interleukin-3 IgG
AB-10610
Alpha Diagnostics
100 ug
EUR 416.4
Mouse Monoclonal Anti-Human Interleukin-4 IgG
AB-10710
Alpha Diagnostics
100 ug
EUR 416.4
Rat Monoclonal Anti-Mouse Interleukin-4 IgG
AB-10810
Alpha Diagnostics
100 ug
EUR 416.4
Mouse Monoclonal Anti-Human Interleukin-6 IgG
AB-10910
Alpha Diagnostics
100 ug
EUR 416.4
Mouse Monoclonal Anti-Human Interleukin-7 IgG
AB-11010
Alpha Diagnostics
100 ug
EUR 416.4
Mouse Monoclonal Anti-Human Interleukin-8 IgG
AB-11110
Alpha Diagnostics
100 ug
EUR 416.4
Mouse Monoclonal Anti-Human Interleukin-10 IgG
AB-11210
Alpha Diagnostics
100 ug
EUR 416.4
One of the major metabolite is stirring the amine of 2,2-dimethyl-5-nitro-2H-benzimidazole (named Sepin-1.55). Sepin-concentration in the blood samples was 1.55 Sepin-1 depending on the dose and used for pharmacokinetic analysis Sepin-1. Tmax was about 5-15 minutes.
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