Separase activity distribution can be a marker of major molecular response and proliferation of CD34+ cells in TKI-treated chronic myeloid leukemia patients.
Sepin-1 is a small compound that inhibits the enzymatic activity of Separase and growth of cancer cells. As part of the IND-enabling studies to develop Sepin-1 as a chemotherapeutic agent, here we have profiled toxicity Sepin-1 in mice Sprague-Dawley in setting good laboratory practice (GLP). The maximum tolerated dose (MTD) of Sepin-1 in mice is 40 mg / kg in a single dose study and 20 mg / kg dose study for 7 days in a row.
Toxicity study consists of two parts-Main Study and Restoration Study. Sepin-1 to 0 (control), 5 (low dose), 10 (median dose), and 20 (high dose) mg / kg given by bolus intravenous injection to mice once a day for 28 consecutive days. The animals were euthanized at the Main Study Day 29, whereas in the study animals were allowed to recover Recovery for 28 days after 28 days Sepin-1 dose before they were euthanized on Day 29 of the off-dose periods.
Although the effects of Sepin-1 in low and median doses were minimal, hematological analysis shows that high doses of Sepin-1 associated with a decrease in red blood cells and hemoglobin, and an increase in the number of reticulocytes and platelets and mean corpuscular volume. Clinical chemistry showed that Sepin-1 causes increases in total bilirubin and a decrease in creatine kinase. histopathological analysis showed Sepin-1 results in minimal bone marrow erythroid hyperplasia, minimal to moderate hematopoiesis extramedullary spleen, minimal depletion of lymphoid spleen, minimal to mild thymic lymphoid depletion, and minimal to rats mild mandibular lymph nodes of lymphoid hyperplasia in men and women on Main Learn.
Those abnormal changes that Sepin-1 depending on the dose and largely reversible after a 28-day recovery period in animals of Recovery Study. Based on our results, we conclude that Sepin-1 at pharmacological dose (5-10 mg / kg) was well-tolerated, with no significant levels of mortality or morbidity, and can be developed as a potential new drug for treating Separase-expressed tumors.
Toxicity study of separase inhibitor-Sepin-1 in Sprague-Dawley rats.
Cohesin cleavage by separase enhanced with different substrate
Chromosome segregation began when a cysteine protease, separase, splitting Scc1 transition subunit of cohesin at the metaphase-to-anaphase. Separase inhibited before metaphase with securin tightly bound protein, which contains motifs separase pseudosubstrate blocking the active site.
To investigate the substrate specificity and regulation separase, here we developed a system to produce recombinant human separase securin free. Using these enzymes, we identified motif Scc1 LPE on a substrate different from the cleavage site and necessary for the rapid and specific cleavage of the substrate. LPE Securin also contain conserved motifs, and we provide evidence that this sequence motif involvement Scc1 separase block LPE. Our results indicate that rapid cohesin cleavage by separase require interaction substrate docking outside the active site. This interaction is blocked by securin, providing a second mechanism which inhibits securin cohesin cleavage.
eat-dose pharmacokinetic study Sepin-1 in mice. Sepin-1 intravenously to mice Sprague-Dawley once a day for 28 days in three different (5, 10 and 20mg / kg) dose. Blood samples were taken after dosing on days 1 and 28. Sepin-1 is not stable in phosphate-buffered saline at the base and stable pH buffer such as citric acid-buffered saline (pH 4.0). UHPLC-MS analysis showed Sepin-1 rapidly metabolized in vivo.
JTC-801
A8456-5.1
ApexBio
10 mM (in 1mL DMSO)
EUR 142.8
Description: JTC 801 is a high affinity, selective KOR-3 (NOP) receptor antagonist (Ki = 8.2 nM). Displays approximately 12.5-, 129- and 1055-fold selectivity over human ?-, ?- and ?-opioid receptors respectively.
JTC-801
A8456-50
ApexBio
50 mg
EUR 393.6
Description: JTC 801 is a high affinity, selective KOR-3 (NOP) receptor antagonist (Ki = 8.2 nM). Displays approximately 12.5-, 129- and 1055-fold selectivity over human ?-, ?- and ?-opioid receptors respectively.
(+)-MK 801 Maleate
A8896-10
ApexBio
10 mg
EUR 126
Description: (+)-MK 801 is a potent antagonist of NMDA with Ki value of 30.5nM [1].MK 801 is a potent anticonvulsant exhibits both anxiolytic and sympathomimetic properties.
(+)-MK 801 Maleate
A8896-5.1
ApexBio
10 mM (in 1mL DMSO)
EUR 135.6
Description: (+)-MK 801 is a potent antagonist of NMDA with Ki value of 30.5nM [1].MK 801 is a potent anticonvulsant exhibits both anxiolytic and sympathomimetic properties.
(+)-MK 801 Maleate
A8896-50
ApexBio
50 mg
EUR 319.2
Description: (+)-MK 801 is a potent antagonist of NMDA with Ki value of 30.5nM [1].MK 801 is a potent anticonvulsant exhibits both anxiolytic and sympathomimetic properties.
(+)-MK 801 Hydrogen Maleate
B2326-25
Biovision
each
EUR 418.8
(+)-MK 801 Hydrogen Maleate
B2326-5
Biovision
each
EUR 157.2
(-)-MK 801 Hydrogen Maleate
B2327-25
Biovision
each
EUR 418.8
(-)-MK 801 Hydrogen Maleate
B2327-5
Biovision
each
EUR 157.2
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC800801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF680 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC800801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF680 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC810801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF680R conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC810801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF680R conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC940801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF594 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC940801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF594 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC700801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF770 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC700801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF770 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC880801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF488A conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC880801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF488A conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC050801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF405M conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC050801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF405M conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC040801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF405S conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC040801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF405S conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC400801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF640R conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC400801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF640R conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCB0801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Biotin conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCAP0801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCAP0801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCA0801-250
Biotium
250uL
EUR 459.6
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), APC conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCB0801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Biotin conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCR0801-250
Biotium
250uL
EUR 459.6
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), RPE conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCP0801-250
Biotium
250uL
EUR 459.6
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), PerCP conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNUM0801-50
Biotium
50uL
EUR 474
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), 1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCH0801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNCH0801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNUB0801-100
Biotium
100uL
EUR 250.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Concentration: 0.2mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNUB0801-500
Biotium
500uL
EUR 549.6
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), Concentration: 0.2mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC610801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF660R conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC610801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF660R conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC550801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF555 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC550801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF555 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC430801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF543 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC430801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF543 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC680801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF568 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC680801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF568 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC470801-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF647 conjugate, Concentration: 0.1mg/mL
PSA (Prostate Specific Antigen)(KLK3/801) Antibody
BNC470801-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against PSA (Prostate Specific Antigen)(KLK3/801), CF647 conjugate, Concentration: 0.1mg/mL
Anti-Human PSA Antibody | MPSA-80A-801
MPSA-80A-801
Immunology Consultants Laboratory
1.0 mg
EUR 334
Description:
Anti-Human PSA Antibody ; MPSA-80A-801 ; Immunology Consultants Laboratory
Host: Mouse
Format: Purified Monoclonal
Product Type: Primary Antibody
Antibody Clonality: Monoclonal
Prostate Specific Antigen (PSA); Clone KLK3/801 (Concentrate)
RA0009-C.1
ScyTek Laboratories
0.1 ml
EUR 150
Prostate Specific Antigen (PSA); Clone KLK3/801 (Concentrate)
RA0009-C.5
ScyTek Laboratories
0.5 ml
EUR 360
Recombinant Streptococcus Pyogenes ftsK Protein (aa 1-801)
VAng-Cr8109-inquire
Creative Biolabs
inquire
Ask for price
Description: Streptococcus Pyogenes serotype M18 DNA translocase FtsK (ftsK), recombinant protein.
Recombinant Neisseria Gonorrhoeae lptD Protein (aa 1-801)
VAng-Wyb2182-inquire
Creative Biolabs
inquire
Ask for price
Description: Neisseria Gonorrhoeae (strain ATCC 700825 / FA 1090) LPS-assembly protein lptD, recombinant protein.
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC941256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF594 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC941256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF594 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC801256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF680 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC801256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF680 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC811256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF680R conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC811256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF680R conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC701256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF770 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC701256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF770 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC881256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF488A conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC881256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF488A conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC051256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF405M conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC051256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF405M conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC041256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF405S conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC041256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF405S conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC401256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF640R conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC401256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF640R conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCB1256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Biotin conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCB1256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Biotin conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCAP1256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCAP1256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCA1256-250
Biotium
250uL
EUR 459.6
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), APC conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCR1256-250
Biotium
250uL
EUR 459.6
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), RPE conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCP1256-250
Biotium
250uL
EUR 459.6
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), PerCP conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNUM1256-50
Biotium
50uL
EUR 474
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), 1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCH1256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNCH1256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNUB1256-100
Biotium
100uL
EUR 250.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Concentration: 0.2mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNUB1256-500
Biotium
500uL
EUR 549.6
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), Concentration: 0.2mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC611256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF660R conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC611256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF660R conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC551256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF555 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC551256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF555 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC431256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF543 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC431256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF543 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC681256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF568 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC681256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF568 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC471256-100
Biotium
100uL
EUR 238.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF647 conjugate, Concentration: 0.1mg/mL
Prostate Specific Antigen (PSA) (KLK3/801 + KLK3/1248) Antibody
BNC471256-500
Biotium
500uL
EUR 652.8
Description: Primary antibody against Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF647 conjugate, Concentration: 0.1mg/mL
Anti-Prostate Specific Antigen Antibody Clone KLK3/801, Unconjugated-100ug
354-MSM2-P1
EnQuireBio
100ug
EUR 513.6
Mouse ACV-AB(Activin AB) ELISA Kit
EM0312
FN Test
96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml
PDGF AB protein
30R-2610
Fitzgerald
10 ug
EUR 430.8
Description: Purified recombinant Human PDGF AB protein
PDGF AB protein
30R-AP003
Fitzgerald
10 ug
EUR 327.6
Description: Purified recombinant Human PDGF AB protein
AB-Pinaca Antibody
abx023942-1mg
Abbexa
1 mg
EUR 744
AB-Pinaca Antibody
abx023943-1mg
Abbexa
1 mg
EUR 744
NGAL (Capture Ab)
20-abx019240
Abbexa
EUR 176.40
EUR 777.60
EUR 260.40
EUR 493.20
EUR 126.00
100 ug
1 mg
200 ug
500 ug
50 ug
NGAL (Capture Ab)
20-abx019241
Abbexa
EUR 176.40
EUR 777.60
EUR 493.20
NGAL (Detection Ab)
abx019242-100ug
Abbexa
100 ug
EUR 777.6
Apoa5 (ab) Antibody
BF0615
Affbiotech
200ul
EUR 540
AB-2950 MPEC
351201
Atto
5unit
EUR 334.8
Description: Super oxide(O2) reaction system L ight Emittingreagent
AB-2960 BactoLumix
3512020
Atto
2unit
EUR 378
Description: Menadione oxidation-reduction reaction system for probiotic measurement
AB-3000B Cellgraph
3600000
Atto
unit
EUR 120
Apoa5 (ab) Antibody
abx010415-100ul
Abbexa
100 ul
EUR 493.2
Activin AB, CF
PR15011CF
Neuromics
5 ug
EUR 577.2
PDGF - AB Human
PR27062
Neuromics
2 ug
EUR 229.2
Ab Rabbit GluR2*
P40014-100uL
Pel-Freez
100uL
Ask for price
Ab Rabbit MARCKS*
P40017-100uL
Pel-Freez
100uL
Ask for price
Ab MS GluR1*
P80000-100uL
Pel-Freez
100uL
Ask for price
Human Serum AB
SC00B14
Neuromics
100 ml
EUR 434.4
AB-2950 MPEC
3512010
Atto
each
EUR 6600
ELISA kit for Mouse ACV-AB (Activin AB) Kit
E-EL-M2660
Elabscience Biotech
1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Mouse ACV-AB (Activin AB) Kit in samples from Serum, Plasma, Cell supernatant
IFN-Gamma ab/ Rat IFN- Gamma ab ELISA Kit
ELA-E1716r
Lifescience Market
96 Tests
EUR 1063.2
ACV-AB ELISA Kit| Mouse Activin AB ELISA Kit
EF012990
Lifescience Market
96 Tests
EUR 826.8
Anti-Prostate Specific Antigen Antibody Clone KLK3/801 + KLK3/1248, Unconjugated-100ug
354-MSM6-P1
EnQuireBio
100ug
EUR 513.6
Human Platelet Derived Growth Factor AB (PDGF-AB) CLIA Kit
abx197488-96tests
Abbexa
96 tests
EUR 990
Rat Platelet-Derived Growth Factor AB (PDGF-AB) CLIA Kit
abx197512-96tests
Abbexa
96 tests
EUR 990
Human Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit
201-12-0138
SunredBio
96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.
Pig Platelet-Derived Growth Factor AB (PDGF-AB) ELISA kit
CSB-EQ027978PI-24T
Cusabio
1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Pig Platelet-Derived Growth Factor AB (PDGF-AB) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Pig Platelet-Derived Growth Factor AB (PDGF-AB) ELISA kit
1-CSB-EQ027978PI
Cusabio
EUR 1080.00
EUR 6571.20
EUR 3480.00
1 plate of 96 wells
10 plates of 96 wells each
5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Pig Platelet-Derived Growth Factor AB (PDGF-AB) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Human Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit
CN-03255H1
ChemNorm
96T
EUR 560.4
Human Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit
CN-03255H2
ChemNorm
48T
EUR 379.2
Rat Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit
CN-01590R1
ChemNorm
96T
EUR 548.4
Rat Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit
CN-01590R2
ChemNorm
48T
EUR 367.2
Mouse Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit
CN-02423M1
ChemNorm
96T
EUR 548.4
Mouse Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit
CN-02423M2
ChemNorm
48T
EUR 367.2
Human Platelet-Derived Growth Factor AB, PDGF-AB ELISA kit
CSB-E04701h-24T
Cusabio
1 plate of 24 wells
EUR 198
Description: Quantitative sandwich ELISA kit for measuring Human Platelet-Derived Growth Factor AB, PDGF-AB in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Human Platelet-Derived Growth Factor AB, PDGF-AB ELISA kit
1-CSB-E04701h
Cusabio
EUR 867.60
EUR 5859.60
EUR 3109.20
1 plate of 96 wells
10 plates of 96 wells each
5 plates of 96 wells each
Description: Quantitative sandwich ELISA kit for measuring Human Platelet-Derived Growth Factor AB, PDGF-AB in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Rat Platelet-Derived Growth Factor AB, PDGF-AB ELISA kit
CSB-E04703r-24T
Cusabio
1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Rat Platelet-Derived Growth Factor AB, PDGF-AB in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Rat Platelet-Derived Growth Factor AB, PDGF-AB ELISA kit
1-CSB-E04703r
Cusabio
EUR 843.60
EUR 5811.60
EUR 3084.00
1 plate of 96 wells
10 plates of 96 wells each
5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat Platelet-Derived Growth Factor AB, PDGF-AB in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Rabbit Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit
CSB-E15910Rb-24T
Cusabio
1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Rabbit Platelet-Derived Growth Factor AB (PDGF-AB) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Rabbit Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit
1-CSB-E15910Rb
Cusabio
EUR 843.60
EUR 5811.60
EUR 3084.00
1 plate of 96 wells
10 plates of 96 wells each
5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rabbit Platelet-Derived Growth Factor AB(PDGF-AB) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Rat PDGF-AB(Platelet-Derived Growth Factor AB) ELISA Kit
ER0056
FN Test
96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 4.688pg/ml
Rabbit PDGF-AB(Platelet Derived Growth Factor AB) ELISA Kit
ERB0095
FN Test
96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rabbit;Sensitivity: 0.938 ng/ml
Rat Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit
GA-E0700RT-48T
GenAsia Biotech
48T
EUR 447.6
Rat Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit
GA-E0700RT-96T
GenAsia Biotech
96T
EUR 730.8
Human Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit
GA-E0076HM-48T
GenAsia Biotech
48T
EUR 346.8
Human Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit
GA-E0076HM-96T
GenAsia Biotech
96T
EUR 559.2
Mouse Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit
GA-E0148MS-48T
GenAsia Biotech
48T
EUR 403.2
Mouse Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit
GA-E0148MS-96T
GenAsia Biotech
96T
EUR 640.8
Human PDGF-AB(Platelet-Derived Growth Factor AB) ELISA Kit
EH0139
FN Test
96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml
Rat Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit
QY-E10952
Qayee Biotechnology
96T
EUR 433.2
Mouse Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit
QY-E21208
Qayee Biotechnology
96T
EUR 433.2
Human Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit
QY-E00586
Qayee Biotechnology
96T
EUR 480
Human Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit
YLA2092HU-48T
Shanghai YL Biotech
48T
EUR 435
Human Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit
YLA2092HU-96T
Shanghai YL Biotech
96T
EUR 562.5
One of the major metabolite is stirring the amine of 2,2-dimethyl-5-nitro-2H-benzimidazole (named Sepin-1.55). Sepin-concentration in the blood samples was 1.55 Sepin-1 depending on the dose and used for pharmacokinetic analysis Sepin-1. Tmax was about 5-15 minutes.
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