Separase activity distribution can be a marker of major molecular response and proliferation of CD34+ cells in TKI-treated chronic myeloid leukemia patients.

Separase activity distribution can be a marker of major molecular response and proliferation of CD34+ cells in TKI-treated chronic myeloid leukemia patients.

Separase, a cysteine ​​endopeptidase, are key players in the mitotic sister chromatid separation, the dynamics of the replication fork, and DNA repair. aberrant expression and / or modified separase proteolytic activity associated with aneuploidy, tumorigenesis, and progression of the disease. Due to genomic instability and clonal evolution of the hallmarks of the progress of chronic myeloid leukemia (CML), we have relatively examined separase proteolytic activity in TKI-treated chronic phase CML.

Separase proteolytic activity was analyzed at the single cell level in 88 clinical samples and in 14 healthy controls by flow cytometric assay. In parallel, the BCR-ABL1 gene expression and replication fork velocity was measured by qRT-PCR and DNA tests fiber, respectively. Separase Activity Distribution (SAD) value that indicates the occurrence separase MNC with increased proteolytic activity in the samples found to be positively correlated with BCR-ABL1 gene expression levels and the loss of MMR (relapses) throughout the routine monitoring of BCR-ABL1.

Analysis of CD34 + cells and MNC fractionated by flow cytometric cell sorting according to their level of activity separase (H- and L-fraction) revealed that the CD34 + cells with high activity levels separase (H-fraction) displayed increased proliferation / survival when compared with with normal cells (L-fraction) separase activity (average 3.3-fold, p = 0.0011). BCR-ABL1 positive effect gene expression in MNC H-fractions over L-fraction (42% vs. 8%, respectively).

In addition, expanded CD34 + cells from H-fraction showed a decrease in the speed of replication forks compared to cells L-fraction (p <0.0001). Our data show an association between high activity separase, the rest of the BCR-ABL1 gene expression, and increased capacity for proliferation in hematopoietic cells in leukemia niche TKI-treated chronic phase CML.

Separase activity distribution can be a marker of major molecular response and proliferation of CD34+ cells in TKI-treated chronic myeloid leukemia patients.
Separase activity distribution can be a marker of major molecular response and proliferation of CD34+ cells in TKI-treated chronic myeloid leukemia patients.

The data set on Separase-Sepin Inhibitor-1 toxicity in organ weights, hematology and clinical parameters in mice Sprague Dawley-.

Separase-Sepin Inhibitor-1 has shown great promise as a chemotherapeutic agent to treat Separase development-overexpressing tumors, however, very little is known about the toxicity profile. Here we present data set organ weights, hematology and clinical chemistry parameters in Sepin-1-treated rats Sprague Dawley-.

The data set is generated from two groups-Main Study Recovery Study and Study, life duration, in 29 and 57 days, respectively. Mice in both groups were covered with 0, 5, 10 and 20 mg / kg Sepin-1 once a day for 28 consecutive days. Blood samples from mice in the Main Study their organs were collected and weighed on day 29. The animals in the study were in a dose Recovery-off period of 28 days after being treated with Sepin-1 for 28 days, and samples of their blood and organ weight data were collected on day 57.

The mice’s body weights in both the Main and Recovery Study is collected twice a week. hematological parameters of samples of whole blood, such as hemoglobin concentration, platelet count and blood cells, etc., are determined. clinical chemistry parameters of serum, such as albumin concentration, glucose, cholesterol, triglycerides, alanine / aspartate aminotransferase, etc., are measured. Further analysis may yield useful information on the toxicity of Sepin-1 in Rat Sprague Dawley-. The data presented here relate to a research article entitled “Toxicity studies separase-Sepin inhibitor-1 in mice Sprague-Dowley”, available in Pathology – Research and Practice Journal

Separase antibody

70R-51689 100 ul
EUR 344.4
Description: Purified Polyclonal Separase antibody

SEPARASE antibody

70R-31054 100 ug
EUR 392.4
Description: Rabbit polyclonal SEPARASE antibody

Separase Antibody

20-abx121903
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Separase Antibody

ABF9195 100 ug
EUR 525.6

Separase Antibody

20-abx215242
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

Separase Antibody

AF9195 200ul
EUR 420

Anti-Phospho-Separase (S801) antibody

STJ91032 200 µl
EUR 236.4
Description: Rabbit polyclonal to Phospho-Separase (S801).

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 418.8

SEPARASE antibody (Ser801)

70R-31053 100 ug
EUR 392.4
Description: Rabbit polyclonal SEPARASE antibody (Ser801)

Separase (pS801) Antibody

20-abx134111
  • EUR 376.80
  • EUR 560.40
  • EUR 243.60
  • 100 ul
  • 200 ul
  • 30 ul

Separase Polyclonal Antibody

ABP52424-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Separase from Human, Mouse. This Separase antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Separase around the non-phosphorylation site of S801

Separase Polyclonal Antibody

ABP52424-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Separase from Human, Mouse. This Separase antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Separase around the non-phosphorylation site of S801

Separase Polyclonal Antibody

ABP52424-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Separase from Human, Mouse. This Separase antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Separase around the non-phosphorylation site of S801

Separase Conjugated Antibody

C44415 100ul
EUR 476.4

Separase Polyclonal Antibody

ES3423-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against Separase from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Separase Polyclonal Antibody

ES3423-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against Separase from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Separase Blocking Peptide

20-abx161616
  • EUR 326.40
  • EUR 493.20
  • 1 mg
  • 5 mg

Separase Blocking Peptide

AF9195-BP 1mg
EUR 234

Separase (Phospho-Ser801) Polyclonal Antibody

12353-100ul 100ul
EUR 302.4

Separase (Phospho-Ser801) Polyclonal Antibody

12353-50ul 50ul
EUR 224.4

Separase (phospho Ser801) Polyclonal Antibody

ABP50519-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Separase phospho Ser801) from Human, Mouse. This Separase phospho Ser801) antibody is for WB , IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Separase around the phosphorylation site of S801

Separase (phospho Ser801) Polyclonal Antibody

ABP50519-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Separase phospho Ser801) from Human, Mouse. This Separase phospho Ser801) antibody is for WB , IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Separase around the phosphorylation site of S801

Separase (phospho Ser801) Polyclonal Antibody

ABP50519-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Separase phospho Ser801) from Human, Mouse. This Separase phospho Ser801) antibody is for WB , IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Separase around the phosphorylation site of S801

Separase (phospho Ser801) Polyclonal Antibody

ES1518-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against Separase (phospho Ser801) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Separase (phospho Ser801) Polyclonal Antibody

ES1518-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against Separase (phospho Ser801) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Separase (pS801) Blocking Peptide

20-abx162232
  • EUR 376.80
  • EUR 610.80
  • 1 mg
  • 5 mg

SEPARASE Cell ELISA Kit

abx595539-96tests 96 tests
EUR 764.4

Polyclonal ESPL1 / Separase Antibody (aa767-816)

APR02989G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ESPL1 / Separase (aa767-816). This antibody is tested and proven to work in the following applications:

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 336

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 336

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 336

SEPARASE Colorimetric Cell-Based ELISA Kit

EKC1516 100ul
EUR 686.4

SEPARASE Colorimetric Cell-Based ELISA Kit (OKAG01028)

OKAG01028 96 Wells
EUR 715.2
Description: Description of target: ;Species reactivity: Human, Mouse;Application: ELISA;Assay info: Assay Type: Cell-Based
Subtype: None
Detection Method: Colorimetric 450 nm;Sensitivity:

SEPARASE (Phospho-Ser801) Colorimetric Cell-Based ELISA Kit

EKC2000 100ul
EUR 686.4

Phospho-SEPARASE (Ser801) Colorimetric Cell-Based ELISA Kit (OKAG01525)

OKAG01525 2 x 96 Wells
EUR 888
Description: Description of target: ;Species reactivity: Human: S801, Mouse: S1189;Application: ELISA;Assay info: Assay Type: Cell-Based
Subtype: Phospho
Detection Method: Colorimetric 450 nm;Sensitivity:

Anti-Anti-SEPT6 antibody antibody

STJ11100949 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody

STJ111369 100 µl
EUR 332.4
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody

STJ111530 100 µl
EUR 332.4

Anti-Anti-SEPT4 Antibody antibody

STJ112276 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody

STJ112609 100 µl
EUR 332.4

Anti-Anti-SEPT11 Antibody antibody

STJ113941 100 µl
EUR 332.4

Anti-Anti-SEPT11 Antibody antibody

STJ114081 100 µl
EUR 332.4

Anti-Anti-SEPT5 Antibody antibody

STJ114819 100 µl
EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody

STJ114828 100 µl
EUR 332.4

Anti-Anti-SEPT7 Antibody antibody

STJ116214 100 µl
EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody

STJ117206 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT12 Antibody antibody

STJ117759 100 µl
EUR 332.4
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody

STJ118549 100 µl
EUR 332.4

Anti-Anti-MARCH6 Antibody antibody

STJ118550 100 µl
EUR 332.4

Anti-Anti-MARCH7 Antibody antibody

STJ118752 100 µl
EUR 332.4

Anti-Anti-SEPT3 Antibody antibody

STJ118990 100 µl
EUR 332.4

Anti-Anti-SEPT2 Antibody antibody

STJ28365 100 µl
EUR 332.4

Anti-Anti-SEPT7 Antibody antibody

STJ28963 100 µl
EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT2 Antibody antibody

STJ25475 100 µl
EUR 332.4

Anti-Anti-SEPT5 Antibody antibody

STJ25477 100 µl
EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody

STJ25479 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT1 antibody antibody

STJ119580 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

Anti-Anti-DDB1 Antibody

A00333 100uL
EUR 546
Description: Rabbit Polyclonal DDB1 Antibody. Validated in IP and tested in Human, Mouse.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-10x96wellstestplate 10x96-wells test plate
EUR 6777.36
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x48wellstestplate 1x48-wells test plate
EUR 663.31
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x96wellstestplate 1x96-wells test plate
EUR 896.16
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-5x96wellstestplate 5x96-wells test plate
EUR 3672.72
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

4-AEA465Hu
  • EUR 6837.60
  • EUR 3613.20
  • EUR 896.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.

ELISA kit for Human Anti-AsAb (Anti-Anti-Sperm Antibody Antibody)

ELK8071 1 plate of 96 wells
EUR 518.4
Description: A competitive Inhibition ELISA kit for detection of Anti-Anti-Sperm Antibody Antibody from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Anti-ZNF660 antibody

44742-100ul 100ul
EUR 302.4

Anti-ZNF660 antibody

44742-50ul 50ul
EUR 224.4

Anti-CCV Antibody

10-2789 1 mg
EUR 217.2
Description: Anti-Canine Corona Virus Antibody

Anti-CCV Antibody

10-2790 1 mg
EUR 217.2
Description: Anti-Canine Corona Virus Antibody

Anti-CDV antibody

10-2791 1 mg
EUR 198
Description: Anti-Canine Distemper Virus antibody

Anti-CDV antibody

10-2792 1 mg
EUR 198
Description: Anti-Canine Distemper Virus antibody

Anti-CDV antibody

10-2793 1 mg
EUR 198
Description: Anti-Canine Distemper Virus antibody

Anti-CDV antibody

10-2794 1 mg
EUR 198
Description: Anti-Canine Distemper Virus antibody

Anti-CPV Antibody

10-2795 500 uig
EUR 165.6
Description: Anti-Canine Parvo Virus Antibody

Anti-CPV Antibody

10-2796 500 ug
EUR 165.6
Description: Anti-Canine Parvo Virus Antibody

Anti-CPV Antibody

10-2797 500 ug
EUR 165.6
Description: Anti-Canine Parvo Virus Antibody

Anti-C.CRP antibody

10-2798 500 ug
EUR 165.6
Description: Anti-Canine CRP antibody

Anti-C.CRP antibody

10-2799 500 ug
EUR 165.6
Description: Anti-Canine CRP antibody

Anti-CHW antibody

10-2800 1 mg
EUR 198
Description: Anti-Canine Heartworm antibody

Anti-FeLV antibody

10-2801 1 mg
EUR 217.2
Description: Anti-Feline Leukemia Virus antibody

Anti-FeLV antibody

10-2802 1 mg
EUR 217.2
Description: Anti-Feline Leukemia Virus antibody

Anti-FeLV antibody

10-2803 1 mg
EUR 217.2
Description: Anti-Feline Leukemia Virus antibody

Anti-PGI antibody

10-2806 1 mg
EUR 502.8
Description: Anti-PGI recombinant antibody

Anti-PGI antibody

10-2807 1 mg
EUR 502.8
Description: Anti-PGI recombinant antibody

Anti-PGII antibody

10-2808 1 mg
EUR 502.8
Description: Anti-PGII recombinant antibody

Anti-PGII antibody

10-2809 1 mg
EUR 502.8
Description: Anti-PGII recombinant antibody

Anti-CHW antibody

10-2810 1 mg
EUR 198
Description: Anti-CHW monoclonal antibody

Anti-Giardia antibody

10-2811 1 mg
EUR 198
Description: Anti-Giardia monoclonal antibody

Anti-Giardia antibody

10-2812 1 mg
EUR 198
Description: Anti-Giardia monoclonal antibody

Anti-TAP1 Antibody

A01123 100ul
EUR 476.4
Description: Rabbit Polyclonal TAP1 Antibody. Validated in IP, IHC, WB and tested in Human, Rat.

Anti-CHD4 Antibody

A01125 100ul
EUR 476.4
Description: Rabbit Polyclonal CHD4 Antibody. Validated in IF, IHC and tested in Human, Mouse.

Anti-NRF1 Antibody

A01129-2 100ug/vial
EUR 400.8

Anti-MEF2C Antibody

A01131-1 100ug/vial
EUR 400.8

Anti-SCN4A Antibody

A01138 100ul
EUR 476.4
Description: Rabbit Polyclonal SCN4A Antibody. Validated in WB and tested in Human.

Anti-MTR Antibody

A01140-2 100ug/vial
EUR 400.8

Anti-IL12B Antibody

A01152-2 100ug/vial
EUR 352.8

Anti-IL12B Antibody

A01152-3 100ug/vial
EUR 400.8

Anti-IL12B Antibody

A01152-4 100ug/vial
EUR 352.8

Anti-IL11 Antibody

A01160-1 100ug/vial
EUR 352.8

Anti-Bak Antibody

A01163 200ug
EUR 626.4
Description: Rabbit Polyclonal Bak Antibody. Validated in IP, IF, IHC, WB and tested in Human.

Anti-PGF Antibody

A01164-1 100ug/vial
EUR 352.8

Anti-PGF Antibody

A01164-2 100ug/vial
EUR 352.8

Anti-CD201 Antibody

A01166 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for CD201 Antibody (PROCR) detection.tested for IHC, WB in Human, Mouse, Rat.

Anti-SERCA2 Antibody

A01176 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for SERCA2 Antibody (ATP2A2) detection.tested for IHC, WB in Human, Mouse, Rat.

Anti-XPA Antibody

A01182 100ul
EUR 476.4
Description: Rabbit Polyclonal XPA Antibody. Validated in IHC, WB and tested in Human.

Anti-XPA Antibody

A01182-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for XPA Antibody (XPA) detection.tested for WB in Human, Mouse.

Anti-XPA Antibody

A01182-2 100ug/vial
EUR 352.8

Anti-BNP Antibody

A01186-1 100ul
EUR 476.4
Description: Rabbit Polyclonal BNP Antibody. Validated in IF, IHC, WB and tested in Mouse, Rat.

Anti-CD1c Antibody

A01188-1 100ug/vial
EUR 352.8

Anti-CDC7 Antibody

A01190 100ul
EUR 476.4
Description: Rabbit Polyclonal CDC7 Antibody. Validated in WB and tested in Human.

Anti-VCAM1 Antibody

A01199 100ug/vial
EUR 400.8

Anti-VCAM1 Antibody

A01199-1 100ug/vial
EUR 352.8

Anti-VCAM1 Antibody

A01199-2 100ug/vial
EUR 400.8

Anti-MAP2 Antibody

A01201 100ug/vial
EUR 352.8

Anti-MAP2 Antibody

A01201-1 100ul
EUR 476.4
Description: Rabbit Polyclonal MAP2 Antibody. Validated in IF, WB and tested in Human, Mouse, Rat.

Anti-RING1B Antibody

A01209-1 100ug
EUR 546
Description: Goat Polyclonal RING1B Antibody. Validated in IF, WB and tested in Human, Mouse, Rat.

Anti-MUC2 Antibody

A01212 100ug/vial
EUR 400.8

Anti-C1INH Antibody

A01221 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for C1INH Antibody (SERPING1) detection.tested for WB in Human.

Anti-WWOX Antibody

A01223-1 100ug/vial
EUR 400.8

Anti-RNF168 Antibody

A01224-1 100ug/vial
EUR 400.8

Anti-HDAC5 Antibody

A01230-5 100ug/vial
EUR 400.8

Anti-Dysferlin Antibody

A01234-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Dysferlin Antibody. Validated in WB and tested in Human, Mouse.

Anti-LPP Antibody

A01240-2 100ug/vial
EUR 400.8

Anti-p57 Antibody

A01244 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for p57 Antibody (CDKN1C) detection.tested for IHC, WB in Human, Mouse, Rat.

Anti-MDC1 Antibody

A01252-2 100ug/vial
EUR 400.8

Anti-FHL Antibody

A01258-1 100ug/vial
EUR 400.8

Anti-FHL Antibody

A01258-2 100ug/vial
EUR 352.8

Anti-ACBP Antibody

A01267-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for ACBP Antibody (DBI) detection. Tested with WB in Human, Mouse, Rat.

Anti-PDK1 Antibody

A01268 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for PDK1 Antibody (PDK1) detection. Tested with WB in Human, Mouse, Rat.

Anti-CD81 Antibody

A01281-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for CD81 Antibody (CD81) detection. Tested with WB in Human, Mouse, Rat.

Anti-CHI3L1 Antibody

A01283-1 100ug/vial
EUR 352.8

Anti-HLF Antibody

A01284-1 100ug/vial
EUR 352.8

Anti-BRD7 Antibody

A01289-1 100ug/vial
EUR 400.8

Anti-Endostatin Antibody

A01302 100ul
EUR 476.4
Description: Rabbit Polyclonal Endostatin Antibody. Validated in IHC and tested in Human.

Anti-COL18A1 Antibody

A01302-1 100ug/vial
EUR 352.8

Anti-SATB1 Antibody

A01312-1 100ug/vial
EUR 400.8

Anti-TCF7 Antibody

A01315-2 100ug/vial
EUR 352.8

Anti-WEE1 Antibody

A01319-1 100ug/vial
EUR 352.8

Anti-CD141 Antibody

A01325 100 ug
EUR 476.4
Description: Rabbit Polyclonal CD141 Antibody. Validated in WB and tested in Human.

Anti-NDRG1 Antibody

A01327-1 100ug/vial
EUR 352.8

Anti-FOXP2 Antibody

A01329-1 100ug/vial
EUR 352.8

Anti-CTRO Antibody

A01331 100ul
EUR 476.4
Description: Rabbit Polyclonal CTRO Antibody. Validated in IHC and tested in Human.

Anti-GOLPH3 Antibody

A01333-1 100ug/vial
EUR 400.8

Anti-Aladin Antibody

A01336 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for Aladin Antibody (AAAS) detection. Tested with WB in Human, Rat.

Anti-DBF4 Antibody

A01348-1 100ul
EUR 476.4
Description: Rabbit Polyclonal DBF4 Antibody. Validated in WB and tested in Human, Mouse.

Anti-EIF4G1 Antibody

A01351-2 100ug/vial
EUR 400.8

Anti-DDT Antibody

A01354 100ug/vial
EUR 400.8

Anti-Cdc6 Antibody

A01355 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for Cdc6 Antibody (CDC6) detection.tested for WB in Human, Mouse.

Anti-TRIM5 Antibody

A01359-1 100ug/vial
EUR 352.8

Anti-STAT2 Antibody

A01360 100ug/vial
EUR 352.8

Anti-CDC45L Antibody

A01367-1 100ug/vial
EUR 352.8

Anti-VAPB Antibody

A01372 100ug/vial
EUR 352.8

Anti-IGFBP2 Antibody

A01373-1 100ug/vial
EUR 400.8

Anti-IGFBP2 Antibody

A01373-2 100ug/vial
EUR 400.8

Anti-SphK2 Antibody

A01382 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for SphK2 Antibody (SPHK2) detection.tested for WB in Human, Mouse, Rat.

Anti-SPHK2 Antibody

A01382-1 100ug/vial
EUR 400.8

Anti-ITK Antibody

A01385-2 100ug/vial
EUR 352.8

Anti-NAT1 Antibody

A01386-1 100ug/vial
EUR 352.8

Anti-Tff1 Antibody

A01391-1 100ug/vial
EUR 352.8

Anti-ALDH1A1 Antibody

A01392 100ug/vial
EUR 400.8

Anti-TIP60 Antibody

A01393 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for TIP60 Antibody (KAT5) detection. Tested with WB in Human, Mouse, Rat.

Anti-LIF Antibody

A01400 100ug/vial
EUR 352.8

Anti-RALBP1 Antibody

A01403-1 100ug/vial
EUR 400.8

Anti-Cav3.2 Antibody

A01406 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for Cav3.2 Antibody (CACNA1H) detection. Tested with IHC in Human, Rat, Mouse.

Anti-CARD9 Antibody

A01410-1 100ug/vial
EUR 400.8

Anti-PRMT1 Antibody

A01417-1 100ug
EUR 476.4
Description: Rabbit Polyclonal PRMT1 Antibody. Validated in ELISA, IHC, WB and tested in Human.

Anti-PRMT1 Antibody

A01417-3 100ug/vial
EUR 352.8

Anti-Lyn Antibody

A01424-2 100ug/vial
EUR 400.8

Anti-IL6R Antibody

A01425-1 100ug/vial
EUR 352.8

Anti-PSD Antibody

A01427 100ug/vial
EUR 352.8

Anti-DDB2 Antibody

A01430-2 100ug/vial
EUR 352.8

Anti-FCGR2A Antibody

A01450-1 100ug/vial
EUR 400.8

Anti-FES Antibody

A01453 100ug/vial
EUR 352.8

Anti-TAK1 Antibody

A01458 100ug/vial
EUR 476.4
Description: Rabbit Polyclonal TAK1 Antibody. Validated in IHC and tested in Human, Mouse, Rat.

Anti-GALT Antibody

A01460-1 100ug/vial
EUR 352.8

Anti-BTG2 Antibody

A01461-1 100ug/vial
EUR 400.8

Anti-GSTA1 Antibody

A01462 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for GSTA1 Antibody (GSTA1) detection.tested for IHC in Human.

Anti-ACVL1 Antibody

A01468-1 100ul
EUR 476.4
Description: Rabbit Polyclonal ACVL1 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-BNIP3 Antibody

A01469 100ug/vial
EUR 352.8

Anti-TRPC3 Antibody

A01472 100ug/vial
EUR 352.8

Anti-ABCG8 Antibody

A01482-1 100ug/vial
EUR 352.8

Anti-ABCG8 Antibody

A01482-2 100ug/vial
EUR 352.8


Separase, a sister chromatid cohesion enzyme-finish, is an oncogene and is expressed in many human cancers. Sepin-1 (2,2-dimethyl-5-nitro-2H-benzimidazole-1,3-dioxide) is a potent inhibitor Separase which inhibit cancer cell growth, cell migration and wound healing, indicating that Sepin-1 has a great potential with a target separase-overexpressing tumors.

Karina

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