Separase activity distribution can be a marker of major molecular response and proliferation of CD34+ cells in TKI-treated chronic myeloid leukemia patients.

Separase activity distribution can be a marker of major molecular response and proliferation of CD34+ cells in TKI-treated chronic myeloid leukemia patients.

Separase, a cysteine ​​endopeptidase, are key players in the mitotic sister chromatid separation, the dynamics of the replication fork, and DNA repair. aberrant expression and / or modified separase proteolytic activity associated with aneuploidy, tumorigenesis, and progression of the disease. Due to genomic instability and clonal evolution of the hallmarks of the progress of chronic myeloid leukemia (CML), we have relatively examined separase proteolytic activity in TKI-treated chronic phase CML.

Separase proteolytic activity was analyzed at the single cell level in 88 clinical samples and in 14 healthy controls by flow cytometric assay. In parallel, the BCR-ABL1 gene expression and replication fork velocity was measured by qRT-PCR and DNA tests fiber, respectively. Separase Activity Distribution (SAD) value that indicates the occurrence separase MNC with increased proteolytic activity in the samples found to be positively correlated with BCR-ABL1 gene expression levels and the loss of MMR (relapses) throughout the routine monitoring of BCR-ABL1.

Analysis of CD34 + cells and MNC fractionated by flow cytometric cell sorting according to their level of activity separase (H- and L-fraction) revealed that the CD34 + cells with high activity levels separase (H-fraction) displayed increased proliferation / survival when compared with with normal cells (L-fraction) separase activity (average 3.3-fold, p = 0.0011). BCR-ABL1 positive effect gene expression in MNC H-fractions over L-fraction (42% vs. 8%, respectively).

In addition, expanded CD34 + cells from H-fraction showed a decrease in the speed of replication forks compared to cells L-fraction (p <0.0001). Our data show an association between high activity separase, the rest of the BCR-ABL1 gene expression, and increased capacity for proliferation in hematopoietic cells in leukemia niche TKI-treated chronic phase CML.

Separase activity distribution can be a marker of major molecular response and proliferation of CD34+ cells in TKI-treated chronic myeloid leukemia patients.
Separase activity distribution can be a marker of major molecular response and proliferation of CD34+ cells in TKI-treated chronic myeloid leukemia patients.

The data set on Separase-Sepin Inhibitor-1 toxicity in organ weights, hematology and clinical parameters in mice Sprague Dawley-.

Separase-Sepin Inhibitor-1 has shown great promise as a chemotherapeutic agent to treat Separase development-overexpressing tumors, however, very little is known about the toxicity profile. Here we present data set organ weights, hematology and clinical chemistry parameters in Sepin-1-treated rats Sprague Dawley-.

The data set is generated from two groups-Main Study Recovery Study and Study, life duration, in 29 and 57 days, respectively. Mice in both groups were covered with 0, 5, 10 and 20 mg / kg Sepin-1 once a day for 28 consecutive days. Blood samples from mice in the Main Study their organs were collected and weighed on day 29. The animals in the study were in a dose Recovery-off period of 28 days after being treated with Sepin-1 for 28 days, and samples of their blood and organ weight data were collected on day 57.

The mice’s body weights in both the Main and Recovery Study is collected twice a week. hematological parameters of samples of whole blood, such as hemoglobin concentration, platelet count and blood cells, etc., are determined. clinical chemistry parameters of serum, such as albumin concentration, glucose, cholesterol, triglycerides, alanine / aspartate aminotransferase, etc., are measured. Further analysis may yield useful information on the toxicity of Sepin-1 in Rat Sprague Dawley-. The data presented here relate to a research article entitled “Toxicity studies separase-Sepin inhibitor-1 in mice Sprague-Dowley”, available in Pathology – Research and Practice Journal

Separase Antibody

44415-100ul 100ul
EUR 252

Separase Antibody

44415-50ul 50ul
EUR 187

Separase Antibody

AF9195 200ul
EUR 304
Description: Separase Antibody detects endogenous levels of total Separase.

Separase Antibody

ABF9195 100 ug
EUR 438

SEPARASE antibody

70R-31054 100 ug
EUR 327
Description: Rabbit polyclonal SEPARASE antibody

Separase antibody

70R-51689 100 ul
EUR 287
Description: Purified Polyclonal Separase antibody

Anti-Phospho-Separase (S801) antibody

STJ91032 200 µl
EUR 197
Description: Rabbit polyclonal to Phospho-Separase (S801).

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

Separase Polyclonal Antibody

ES3423-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Separase from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Separase Polyclonal Antibody

ES3423-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Separase from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Separase (pS801) Antibody

20-abx134111
  • EUR 314.00
  • EUR 467.00
  • EUR 203.00
  • 100 ul
  • 200 ul
  • 30 ul

Separase Polyclonal Antibody

ABP52424-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of Separase from Human, Mouse. This Separase antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Separase around the non-phosphorylation site of S801

Separase Polyclonal Antibody

ABP52424-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of Separase from Human, Mouse. This Separase antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Separase around the non-phosphorylation site of S801

Separase Polyclonal Antibody

ABP52424-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of Separase from Human, Mouse. This Separase antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Separase around the non-phosphorylation site of S801

Separase Conjugated Antibody

C44415 100ul
EUR 397

SEPARASE antibody (Ser801)

70R-31053 100 ug
EUR 327
Description: Rabbit polyclonal SEPARASE antibody (Ser801)

Separase Blocking Peptide

20-abx161616
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg

Separase Blocking Peptide

AF9195-BP 1mg
EUR 195

Separase (phospho Ser801) Polyclonal Antibody

ES1518-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Separase (phospho Ser801) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Separase (phospho Ser801) Polyclonal Antibody

ES1518-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Separase (phospho Ser801) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Separase (phospho Ser801) Polyclonal Antibody

ABP50519-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of Separase phospho Ser801) from Human, Mouse. This Separase phospho Ser801) antibody is for WB , IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Separase around the phosphorylation site of S801

Separase (phospho Ser801) Polyclonal Antibody

ABP50519-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of Separase phospho Ser801) from Human, Mouse. This Separase phospho Ser801) antibody is for WB , IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Separase around the phosphorylation site of S801

Separase (phospho Ser801) Polyclonal Antibody

ABP50519-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of Separase phospho Ser801) from Human, Mouse. This Separase phospho Ser801) antibody is for WB , IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Separase around the phosphorylation site of S801

Separase (Phospho-Ser801) Polyclonal Antibody

12353-100ul 100ul
EUR 252

Separase (Phospho-Ser801) Polyclonal Antibody

12353-50ul 50ul
EUR 187

SEPARASE Cell ELISA Kit

abx595539-96tests 96 tests
EUR 637

Separase (pS801) Blocking Peptide

20-abx162232
  • EUR 314.00
  • EUR 509.00
  • 1 mg
  • 5 mg

Polyclonal ESPL1 / Separase Antibody (aa767-816)

APR02989G 0.05ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ESPL1 / Separase (aa767-816). This antibody is tested and proven to work in the following applications:

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

SEPARASE Colorimetric Cell-Based ELISA Kit

EKC1516 100ul
EUR 572

SEPARASE Colorimetric Cell-Based ELISA Kit (OKAG01028)

OKAG01028 96 Wells
EUR 596
Description: Description of target: ;Species reactivity: Human, Mouse;Application: ELISA;Assay info: Assay Type: Cell-Based
Subtype: None
Detection Method: Colorimetric 450 nm;Sensitivity:

SEPARASE (Phospho-Ser801) Colorimetric Cell-Based ELISA Kit

EKC2000 100ul
EUR 572

Phospho-SEPARASE (Ser801) Colorimetric Cell-Based ELISA Kit (OKAG01525)

OKAG01525 2 x 96 Wells
EUR 740
Description: Description of target: ;Species reactivity: Human: S801, Mouse: S1189;Application: ELISA;Assay info: Assay Type: Cell-Based
Subtype: Phospho
Detection Method: Colorimetric 450 nm;Sensitivity:

Anti-Anti-SEPT6 antibody antibody

STJ11100949 100 µl
EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody

STJ111369 100 µl
EUR 277
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody

STJ111530 100 µl
EUR 277

Anti-Anti-SEPT4 Antibody antibody

STJ112276 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody

STJ112609 100 µl
EUR 277

Anti-Anti-SEPT2 Antibody antibody

STJ25475 100 µl
EUR 277

Anti-Anti-SEPT5 Antibody antibody

STJ25477 100 µl
EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody

STJ25479 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT2 Antibody antibody

STJ28365 100 µl
EUR 277

Anti-Anti-SEPT7 Antibody antibody

STJ28963 100 µl
EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT7 Antibody antibody

STJ116214 100 µl
EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody

STJ117206 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT12 Antibody antibody

STJ117759 100 µl
EUR 277
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody

STJ118549 100 µl
EUR 277

Anti-Anti-MARCH6 Antibody antibody

STJ118550 100 µl
EUR 277

Anti-Anti-MARCH7 Antibody antibody

STJ118752 100 µl
EUR 277

Anti-Anti-SEPT3 Antibody antibody

STJ118990 100 µl
EUR 277

Anti-Anti-SEPT1 antibody antibody

STJ119580 100 µl
EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

Anti-Anti-SEPT11 Antibody antibody

STJ113941 100 µl
EUR 277

Anti-Anti-SEPT11 Antibody antibody

STJ114081 100 µl
EUR 277

Anti-Anti-SEPT5 Antibody antibody

STJ114819 100 µl
EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody

STJ114828 100 µl
EUR 277

Anti-Anti-DDB1 Antibody

A00333 100uL
EUR 455
Description: Rabbit Polyclonal DDB1 Antibody. Validated in IP and tested in Human, Mouse.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-10x96wellstestplate 10x96-wells test plate
EUR 5647.8
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x48wellstestplate 1x48-wells test plate
EUR 552.76
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x96wellstestplate 1x96-wells test plate
EUR 746.8
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-5x96wellstestplate 5x96-wells test plate
EUR 3060.6
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

4-AEA465Hu
  • EUR 5698.00
  • EUR 3011.00
  • EUR 747.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.

ELISA kit for Human Anti-AsAb (Anti-Anti-Sperm Antibody Antibody)

ELK8071 1 plate of 96 wells
EUR 432
Description: A competitive Inhibition ELISA kit for detection of Anti-Anti-Sperm Antibody Antibody from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Anti-MeCP2 Antibody

M00047-1 100ul
EUR 397
Description: Rabbit Polyclonal MeCP2 Antibody. Validated in IHC, WB and tested in Human, Monkey, Mouse, Rat.

Anti-GAPDH Antibody

M00227-4 100ul
EUR 397
Description: Rabbit Polyclonal GAPDH Antibody. Validated in IF, IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat.

Anti-Vimentin Antibody

M00235-4 100ul
EUR 397
Description: Rabbit Polyclonal Vimentin Antibody. Validated in IHC, WB and tested in Bovine, Equine, Human, Mouse, Pig, Rat.

Anti-Vimentin Antibody

M00235-5 100ul
EUR 397
Description: Chicken Polyclonal Vimentin Antibody. Validated in IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat.

Anti-CNP Antibody

M01017-2 100ul
EUR 397
Description: Rabbit Polyclonal CNP Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-CNP Antibody

M01017-3 100ul
EUR 397
Description: Chicken Polyclonal CNP Antibody. Validated in IHC, WB and tested in Equine, Pig.

Anti-GAP43 Antibody

M01868-3 100ul
EUR 397
Description: Rabbit Polyclonal GAP43 Antibody. Validated in IF, IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat.

Anti-GAP43 Antibody

M01868-4 100ul
EUR 397
Description: Chicken Polyclonal GAP43 Antibody. Validated in IF, IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat.

Anti-GPSN2 Antibody

F08289-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for GPSN2 Antibody (TECR) detection.tested for WB in Human, Mouse, Rat.

Anti-Calbindin Antibody

M03047-2 100ul
EUR 397
Description: Chicken Polyclonal Calbindin Antibody. Validated in IF, IHC, WB and tested in Bovine, Human, Mouse, Rat.

Anti-Fibrillarin Antibody

M03178-4 100ul
EUR 397
Description: Rabbit Polyclonal Fibrillarin Antibody. Validated in IP, IHC, WB and tested in Human, Mouse, Rat.

Anti-Fibrillarin Antibody

M03178-5 100ul
EUR 397
Description: Chicken Polyclonal Fibrillarin Antibody. Validated in IF, IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat.

Anti-Parvalbumin Antibody

M04041-2 100ul
EUR 397
Description: Chicken Polyclonal Parvalbumin Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat.

Anti-Calretinin Antibody

M04255-3 100ul
EUR 397
Description: Rabbit Polyclonal Calretinin Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-Calretinin Antibody

M04255-4 100ul
EUR 397
Description: Chicken Polyclonal Calretinin Antibody. Validated in IF, IHC, WB and tested in Bovine, Equine, Human, Mouse, Pig, Rat.

Anti-Laminin Antibody

M04965 100ul
EUR 397
Description: Rabbit Polyclonal Laminin Antibody. Validated in IHC and tested in Human, Mouse, Rat.

Anti-Secretagogin Antibody

M10629-1 100ul
EUR 397
Description: Rabbit Polyclonal Secretagogin Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat.

Anti-Secretagogin Antibody

M10629-2 100ul
EUR 397
Description: Chicken Polyclonal Secretagogin Antibody. Validated in IF, IHC, WB and tested in Bovine, Human, Mouse, Rat.

Anti-ATF6 Antibody

PA1011 100ug/vial
EUR 334

Anti-ATF6 Antibody

PA1011-1 100ug/vial
EUR 294

Anti-ATP5J Antibody

PA1012 100ug/vial
EUR 294

Anti-Bax Antibody

PA1013 100ug/vial
EUR 294

Anti-Bax Antibody

PA1013-1 100ug/vial
EUR 294

Anti-BDNF Antibody

PA1014 100ug/vial
EUR 294

Anti-CCR5 Antibody

PA1016 100ug/vial
EUR 294

Anti-CCR5 Antibody

PA1016-1 100ug/vial
EUR 294

Anti-CCR5 Antibody

PA1016-2 100ug/vial
EUR 294

Anti-CCR7 Antibody

PA1017 100ug/vial
EUR 294

Anti-CD22 Antibody

PA1018 100ug/vial
EUR 334

Anti-CD22 Antibody

PA1018-1 100ug/vial
EUR 334


Separase, a sister chromatid cohesion enzyme-finish, is an oncogene and is expressed in many human cancers. Sepin-1 (2,2-dimethyl-5-nitro-2H-benzimidazole-1,3-dioxide) is a potent inhibitor Separase which inhibit cancer cell growth, cell migration and wound healing, indicating that Sepin-1 has a great potential with a target separase-overexpressing tumors.

Karina

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