Separase activity distribution can be a marker of major molecular response and proliferation of CD34+ cells in TKI-treated chronic myeloid leukemia patients.

Separase activity distribution can be a marker of major molecular response and proliferation of CD34+ cells in TKI-treated chronic myeloid leukemia patients.

Separase, a cysteine ​​endopeptidase, are key players in the mitotic sister chromatid separation, the dynamics of the replication fork, and DNA repair. aberrant expression and / or modified separase proteolytic activity associated with aneuploidy, tumorigenesis, and progression of the disease. Due to genomic instability and clonal evolution of the hallmarks of the progress of chronic myeloid leukemia (CML), we have relatively examined separase proteolytic activity in TKI-treated chronic phase CML.

Separase proteolytic activity was analyzed at the single cell level in 88 clinical samples and in 14 healthy controls by flow cytometric assay. In parallel, the BCR-ABL1 gene expression and replication fork velocity was measured by qRT-PCR and DNA tests fiber, respectively. Separase Activity Distribution (SAD) value that indicates the occurrence separase MNC with increased proteolytic activity in the samples found to be positively correlated with BCR-ABL1 gene expression levels and the loss of MMR (relapses) throughout the routine monitoring of BCR-ABL1.

Analysis of CD34 + cells and MNC fractionated by flow cytometric cell sorting according to their level of activity separase (H- and L-fraction) revealed that the CD34 + cells with high activity levels separase (H-fraction) displayed increased proliferation / survival when compared with with normal cells (L-fraction) separase activity (average 3.3-fold, p = 0.0011). BCR-ABL1 positive effect gene expression in MNC H-fractions over L-fraction (42% vs. 8%, respectively).

In addition, expanded CD34 + cells from H-fraction showed a decrease in the speed of replication forks compared to cells L-fraction (p <0.0001). Our data show an association between high activity separase, the rest of the BCR-ABL1 gene expression, and increased capacity for proliferation in hematopoietic cells in leukemia niche TKI-treated chronic phase CML.

Separase activity distribution can be a marker of major molecular response and proliferation of CD34+ cells in TKI-treated chronic myeloid leukemia patients.
Separase activity distribution can be a marker of major molecular response and proliferation of CD34+ cells in TKI-treated chronic myeloid leukemia patients.

The data set on Separase-Sepin Inhibitor-1 toxicity in organ weights, hematology and clinical parameters in mice Sprague Dawley-.

Separase-Sepin Inhibitor-1 has shown great promise as a chemotherapeutic agent to treat Separase development-overexpressing tumors, however, very little is known about the toxicity profile. Here we present data set organ weights, hematology and clinical chemistry parameters in Sepin-1-treated rats Sprague Dawley-.

The data set is generated from two groups-Main Study Recovery Study and Study, life duration, in 29 and 57 days, respectively. Mice in both groups were covered with 0, 5, 10 and 20 mg / kg Sepin-1 once a day for 28 consecutive days. Blood samples from mice in the Main Study their organs were collected and weighed on day 29. The animals in the study were in a dose Recovery-off period of 28 days after being treated with Sepin-1 for 28 days, and samples of their blood and organ weight data were collected on day 57.

The mice’s body weights in both the Main and Recovery Study is collected twice a week. hematological parameters of samples of whole blood, such as hemoglobin concentration, platelet count and blood cells, etc., are determined. clinical chemistry parameters of serum, such as albumin concentration, glucose, cholesterol, triglycerides, alanine / aspartate aminotransferase, etc., are measured. Further analysis may yield useful information on the toxicity of Sepin-1 in Rat Sprague Dawley-. The data presented here relate to a research article entitled “Toxicity studies separase-Sepin inhibitor-1 in mice Sprague-Dowley”, available in Pathology – Research and Practice Journal

SEPARASE antibody

70R-31054 100 ug
EUR 392.4
Description: Rabbit polyclonal SEPARASE antibody

Separase Antibody

44415-100ul 100ul
EUR 302.4

Separase Antibody

44415-50ul 50ul
EUR 224.4

Separase Antibody

20-abx121903
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Separase Antibody

ABF9195 100 ug
EUR 525.6

Separase Antibody

20-abx215242
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

Anti-Phospho-Separase (S801) antibody

STJ91032 200 µl
EUR 236.4
Description: Rabbit polyclonal to Phospho-Separase (S801).

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 418.8

Separase Polyclonal Antibody

ABP52424-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Separase from Human, Mouse. This Separase antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Separase around the non-phosphorylation site of S801

Separase Polyclonal Antibody

ABP52424-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Separase from Human, Mouse. This Separase antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Separase around the non-phosphorylation site of S801

Separase Polyclonal Antibody

ABP52424-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Separase from Human, Mouse. This Separase antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Separase around the non-phosphorylation site of S801

Separase Conjugated Antibody

C44415 100ul
EUR 476.4

Separase Polyclonal Antibody

ES3423-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against Separase from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Separase Polyclonal Antibody

ES3423-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against Separase from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

SEPARASE antibody (Ser801)

70R-31053 100 ug
EUR 392.4
Description: Rabbit polyclonal SEPARASE antibody (Ser801)

Separase (pS801) Antibody

20-abx134111
  • EUR 376.80
  • EUR 560.40
  • EUR 243.60
  • 100 ul
  • 200 ul
  • 30 ul

Separase Blocking Peptide

AF9195-BP 1mg
EUR 234

Separase Blocking Peptide

20-abx161616
  • EUR 326.40
  • EUR 493.20
  • 1 mg
  • 5 mg

Separase (phospho Ser801) Polyclonal Antibody

ABP50519-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Separase phospho Ser801) from Human, Mouse. This Separase phospho Ser801) antibody is for WB , IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Separase around the phosphorylation site of S801

Separase (phospho Ser801) Polyclonal Antibody

ABP50519-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Separase phospho Ser801) from Human, Mouse. This Separase phospho Ser801) antibody is for WB , IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Separase around the phosphorylation site of S801

Separase (phospho Ser801) Polyclonal Antibody

ABP50519-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Separase phospho Ser801) from Human, Mouse. This Separase phospho Ser801) antibody is for WB , IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Separase around the phosphorylation site of S801

Separase (phospho Ser801) Polyclonal Antibody

ES1518-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against Separase (phospho Ser801) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Separase (phospho Ser801) Polyclonal Antibody

ES1518-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against Separase (phospho Ser801) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Separase (Phospho-Ser801) Polyclonal Antibody

12353-100ul 100ul
EUR 302.4

Separase (Phospho-Ser801) Polyclonal Antibody

12353-50ul 50ul
EUR 224.4

Separase (pS801) Blocking Peptide

20-abx162232
  • EUR 376.80
  • EUR 610.80
  • 1 mg
  • 5 mg

SEPARASE Cell ELISA Kit

abx595539-96tests 96 tests
EUR 764.4

Polyclonal ESPL1 / Separase Antibody (aa767-816)

APR02989G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ESPL1 / Separase (aa767-816). This antibody is tested and proven to work in the following applications:

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 336

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 336

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 336

SEPARASE Colorimetric Cell-Based ELISA Kit

EKC1516 100ul
EUR 686.4

SEPARASE Colorimetric Cell-Based ELISA Kit (OKAG01028)

OKAG01028 96 Wells
EUR 715.2
Description: Description of target: ;Species reactivity: Human, Mouse;Application: ELISA;Assay info: Assay Type: Cell-Based
Subtype: None
Detection Method: Colorimetric 450 nm;Sensitivity:

SEPARASE (Phospho-Ser801) Colorimetric Cell-Based ELISA Kit

EKC2000 100ul
EUR 686.4

Phospho-SEPARASE (Ser801) Colorimetric Cell-Based ELISA Kit (OKAG01525)

OKAG01525 2 x 96 Wells
EUR 888
Description: Description of target: ;Species reactivity: Human: S801, Mouse: S1189;Application: ELISA;Assay info: Assay Type: Cell-Based
Subtype: Phospho
Detection Method: Colorimetric 450 nm;Sensitivity:

Anti-Anti-SEPT6 antibody antibody

STJ11100949 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody

STJ111369 100 µl
EUR 332.4
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody

STJ111530 100 µl
EUR 332.4

Anti-Anti-SEPT4 Antibody antibody

STJ112276 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody

STJ112609 100 µl
EUR 332.4

Anti-Anti-SEPT2 Antibody antibody

STJ25475 100 µl
EUR 332.4

Anti-Anti-SEPT5 Antibody antibody

STJ25477 100 µl
EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody

STJ25479 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT2 Antibody antibody

STJ28365 100 µl
EUR 332.4

Anti-Anti-SEPT7 Antibody antibody

STJ28963 100 µl
EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT1 antibody antibody

STJ119580 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

Anti-Anti-SEPT12 Antibody antibody

STJ117759 100 µl
EUR 332.4
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody

STJ118549 100 µl
EUR 332.4

Anti-Anti-MARCH6 Antibody antibody

STJ118550 100 µl
EUR 332.4

Anti-Anti-MARCH7 Antibody antibody

STJ118752 100 µl
EUR 332.4

Anti-Anti-SEPT3 Antibody antibody

STJ118990 100 µl
EUR 332.4

Anti-Anti-SEPT11 Antibody antibody

STJ113941 100 µl
EUR 332.4

Anti-Anti-SEPT11 Antibody antibody

STJ114081 100 µl
EUR 332.4

Anti-Anti-SEPT5 Antibody antibody

STJ114819 100 µl
EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody

STJ114828 100 µl
EUR 332.4

Anti-Anti-SEPT7 Antibody antibody

STJ116214 100 µl
EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody

STJ117206 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-DDB1 Antibody

A00333 100uL
EUR 546
Description: Rabbit Polyclonal DDB1 Antibody. Validated in IP and tested in Human, Mouse.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-10x96wellstestplate 10x96-wells test plate
EUR 6777.36
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x48wellstestplate 1x48-wells test plate
EUR 663.31
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x96wellstestplate 1x96-wells test plate
EUR 896.16
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-5x96wellstestplate 5x96-wells test plate
EUR 3672.72
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

4-AEA465Hu
  • EUR 6837.60
  • EUR 3613.20
  • EUR 896.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.

ELISA kit for Human Anti-AsAb (Anti-Anti-Sperm Antibody Antibody)

ELK8071 1 plate of 96 wells
EUR 518.4
Description: A competitive Inhibition ELISA kit for detection of Anti-Anti-Sperm Antibody Antibody from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Anti-H4K20me1 Antibody

CI1005 100ul
EUR 589.2
Description: Rabbit Polyclonal H4K20me1 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human.

Anti-H4K20me3 Antibody

CI1011 100ul
EUR 589.2
Description: Rabbit Polyclonal H4K20me3 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human.

Anti-TIP5 Antibody

CI1016 100ul
EUR 589.2
Description: Rabbit Polyclonal TIP5 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human, Mouse.

Anti-H4K8ac Antibody

CI1021 100ul
EUR 589.2
Description: Rabbit Polyclonal H4K8ac Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human.

Anti-MYH11 Antibody

CI1028 100ul
EUR 589.2
Description: Rabbit Polyclonal MYH11 Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IHC, WB and tested in Human.

Anti-Ski3 Antibody

CI1031 150ug/50ul
EUR 589.2
Description: Rabbit Polyclonal Ski3 Antibody. Validated in ChIP, ChIP-qPCR, IF, IHC, WB and tested in Human.

Anti-Ski8 Antibody

CI1032 150ug/60ul
EUR 589.2
Description: Rabbit Polyclonal Ski8 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Drosophila, Human.

Anti-H4K5,8,12ac Antibody

CI1033 50ug/66ul
EUR 589.2
Description: Rabbit Polyclonal H4K5,8,12ac Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IF, IHC, WB and tested in Human, Mouse.

Anti-H4K5,8,12,16ac Antibody

CI1035 50ug/66ul
EUR 589.2
Description: Rabbit Polyclonal H4K5,8,12,16ac Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IF, IHC, WB and tested in Human, Mouse.

Anti-H4K5ac Antibody

CI1036 50ug/28ul
EUR 589.2
Description: Rabbit Polyclonal H4K5ac Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IHC, WB and tested in Human, Mouse.

Anti-H4K20me1 Antibody

CI1039 50ug/25ul
EUR 589.2
Description: Rabbit Polyclonal H4K20me1 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human.

Anti-MeCP2 Antibody

CI1047 50ug/42ul
EUR 589.2
Description: Rabbit Polyclonal MeCP2 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human.

Anti-H4K20me3 Antibody

CI1050 50ug/47ul
EUR 589.2
Description: Rabbit Polyclonal H4K20me3 Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, Flow Cytometry, IF, IHC, WB and tested in Human, Mouse.

Anti-H3K27me3 Antibody

CI1056 50ug/34ul
EUR 589.2
Description: Rabbit Polyclonal H3K27me3 Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IF, IHC, WB and tested in Arabidopsis, Drosophila, Human, Mouse, Rat, Schistosoma, Zebrafish.

Anti-MBD1 Antibody

CI1058 50ug/72ul
EUR 589.2
Description: Rabbit Polyclonal MBD1 Antibody. Validated in ChIP, ChIP-qPCR, Flow Cytometry, WB and tested in Human, Mouse.

Anti-p53 Antibody

CI1060 50ug/50ul
EUR 589.2
Description: Rabbit Polyclonal p53 Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, Flow Cytometry, IHC, WB and tested in Human.

Anti-H4K8ac Antibody

CI1066 50ug/41ul
EUR 589.2
Description: Rabbit Polyclonal H4K8ac Antibody. Validated in ChIP, ChIP-qPCR, Flow Cytometry, IF, IHC, WB and tested in Human, Mouse.

Anti-H4pan Antibody

CI1069 50ug/44ul
EUR 589.2
Description: Rabbit Polyclonal H4pan Antibody. Validated in ChIP, ChIP-qPCR, Flow Cytometry, WB and tested in Human.

Anti-H2AK5ac Antibody

CI1078 50ug/ 54ul
EUR 589.2
Description: Rabbit Polyclonal H2AK5ac Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IHC, WB and tested in Human.

Antibody Anti-cKit

CKITACPO 0,1 mg
EUR 379.8

anti- LIN28B antibody

FNab04785 100µg
EUR 658.5
Description: Antibody raised against LIN28B

anti- LIN41 antibody

FNab04787 100µg
EUR 658.5
Description: Antibody raised against LIN41

anti- LIN7A antibody

FNab04788 100µg
EUR 702
Description: Antibody raised against LIN7A

anti- LIN7B antibody

FNab04789 100µg
EUR 658.5
Description: Antibody raised against LIN7B

anti- LIN7C antibody

FNab04790 100µg
EUR 658.5
Description: Antibody raised against LIN7C

anti- LIN9 antibody

FNab04791 100µg
EUR 606.3
Description: Antibody raised against LIN9

anti- LINGO1 antibody

FNab04792 100µg
EUR 658.5
Description: Antibody raised against LINGO1

anti- LIPA antibody

FNab04793 100µg
EUR 606.3
Description: Antibody raised against LIPA

anti- LIPC antibody

FNab04794 100µg
EUR 606.3
Description: Antibody raised against LIPC

anti- LIPH antibody

FNab04795 100µg
EUR 606.3
Description: Antibody raised against LIPH

anti- LIPI antibody

FNab04796 100µg
EUR 702
Description: Antibody raised against LIPI

anti- LITAF antibody

FNab04798 100µg
EUR 606.3
Description: Antibody raised against LITAF

anti- LKB1 antibody

FNab04802 100µg
EUR 658.5
Description: Antibody raised against LKB1

anti- LMAN1 antibody

FNab04803 100µg
EUR 658.5
Description: Antibody raised against LMAN1

anti- LMBR1L antibody

FNab04804 100µg
EUR 658.5
Description: Antibody raised against LMBR1L

anti- LMF1 antibody

FNab04805 100µg
EUR 606.3
Description: Antibody raised against LMF1

anti- LMF2 antibody

FNab04806 100µg
EUR 606.3
Description: Antibody raised against LMF2

anti- LMNB2 antibody

FNab04807 100µg
EUR 606.3
Description: Antibody raised against LMNB2

anti- LMOD1 antibody

FNab04808 100µg
EUR 606.3
Description: Antibody raised against LMOD1

anti- LMOD3 antibody

FNab04809 100µg
EUR 658.5
Description: Antibody raised against LMOD3

anti- LMP2 antibody

FNab04810 100µg
EUR 606.3
Description: Antibody raised against LMP2

anti- LMP7 antibody

FNab04811 100µg
EUR 658.5
Description: Antibody raised against LMP7

anti- LMX1B antibody

FNab04812 100µg
EUR 606.3
Description: Antibody raised against LMX1B

anti- LNPEP antibody

FNab04813 100µg
EUR 702
Description: Antibody raised against LNPEP

anti- LNX1 antibody

FNab04814 100µg
EUR 658.5
Description: Antibody raised against LNX1

anti- LOC123688 antibody

FNab04815 100µg
EUR 658.5
Description: Antibody raised against LOC123688

anti- LOC286135 antibody

FNab04816 100µg
EUR 658.5
Description: Antibody raised against LOC286135

anti- LOC55908 antibody

FNab04817 100µg
EUR 702
Description: Antibody raised against LOC55908

anti- LOC84740 antibody

FNab04818 100µg
EUR 702
Description: Antibody raised against LOC84740

anti- LOH12CR1 antibody

FNab04819 100µg
EUR 606.3
Description: Antibody raised against LOH12CR1

anti- LONP1 antibody

FNab04820 100µg
EUR 606.3
Description: Antibody raised against LONP1

anti- LONP1 antibody

FNab04821 100µg
EUR 702
Description: Antibody raised against LONP1

anti- Loricrin antibody

FNab04822 100µg
EUR 702
Description: Antibody raised against Loricrin

anti- LOX antibody

FNab04823 100µg
EUR 658.5
Description: Antibody raised against LOX

anti- LPAR4 antibody

FNab04824 100µg
EUR 606.3
Description: Antibody raised against LPAR4

anti- LPCAT1 antibody

FNab04825 100µg
EUR 658.5
Description: Antibody raised against LPCAT1

anti- LPCAT1 antibody

FNab04826 100µg
EUR 702
Description: Antibody raised against LPCAT1

anti- LPCAT2 antibody

FNab04827 100µg
EUR 658.5
Description: Antibody raised against LPCAT2

anti- LPCAT4 antibody

FNab04828 100µg
EUR 606.3
Description: Antibody raised against LPCAT4

anti- LPHN3 antibody

FNab04829 100µg
EUR 606.3
Description: Antibody raised against LPHN3

anti- LPIN2 antibody

FNab04830 100µg
EUR 702
Description: Antibody raised against LPIN2

anti- LPL antibody

FNab04831 100µg
EUR 606.3
Description: Antibody raised against LPL

anti- LPO antibody

FNab04834 100µg
EUR 658.5
Description: Antibody raised against LPO

anti- LPP antibody

FNab04835 100µg
EUR 702
Description: Antibody raised against LPP

anti- LPPR2 antibody

FNab04836 100µg
EUR 702
Description: Antibody raised against LPPR2

anti- LPXN antibody

FNab04837 100µg
EUR 606.3
Description: Antibody raised against LPXN

anti- LRAT antibody

FNab04838 100µg
EUR 606.3
Description: Antibody raised against LRAT

anti- LRCH1 antibody

FNab04839 100µg
EUR 702
Description: Antibody raised against LRCH1

anti- LRCH2 antibody

FNab04840 100µg
EUR 658.5
Description: Antibody raised against LRCH2

anti- LRCH3 antibody

FNab04841 100µg
EUR 606.3
Description: Antibody raised against LRCH3

anti- LRDD antibody

FNab04842 100µg
EUR 606.3
Description: Antibody raised against LRDD

anti- LRG1 antibody

FNab04843 100µg
EUR 702
Description: Antibody raised against LRG1

anti- LRMP antibody

FNab04844 100µg
EUR 702
Description: Antibody raised against LRMP

anti- LRMP antibody

FNab04845 100µg
EUR 702
Description: Antibody raised against LRMP

anti- LRP2BP antibody

FNab04846 100µg
EUR 606.3
Description: Antibody raised against LRP2BP

anti- LRP5 antibody

FNab04848 100µg
EUR 702
Description: Antibody raised against LRP5

anti- LRPAP1 antibody

FNab04849 100µg
EUR 702
Description: Antibody raised against LRPAP1

anti- LRPPRC antibody

FNab04850 100µg
EUR 606.3
Description: Antibody raised against LRPPRC

anti- LRRC1 antibody

FNab04852 100µg
EUR 658.5
Description: Antibody raised against LRRC1

anti- LRRC10 antibody

FNab04853 100µg
EUR 658.5
Description: Antibody raised against LRRC10

anti- LRRC18 antibody

FNab04854 100µg
EUR 658.5
Description: Antibody raised against LRRC18

anti- LRRC20 antibody

FNab04855 100µg
EUR 658.5
Description: Antibody raised against LRRC20

anti- LRRC29 antibody

FNab04856 100µg
EUR 702
Description: Antibody raised against LRRC29

anti- LRRC41 antibody

FNab04857 100µg
EUR 606.3
Description: Antibody raised against LRRC41

anti- LRRC47 antibody

FNab04858 100µg
EUR 658.5
Description: Antibody raised against LRRC47

anti- LRRC4C antibody

FNab04859 100µg
EUR 658.5
Description: Antibody raised against LRRC4C

anti- LRRC52 antibody

FNab04860 100µg
EUR 658.5
Description: Antibody raised against LRRC52

anti- LRRC8C antibody

FNab04861 100µg
EUR 606.3
Description: Antibody raised against LRRC8C

anti- LRRC8D antibody

FNab04862 100µg
EUR 606.3
Description: Antibody raised against LRRC8D

anti- LRRTM1 antibody

FNab04863 100µg
EUR 606.3
Description: Antibody raised against LRRTM1

anti- LRRTM2 antibody

FNab04864 100µg
EUR 658.5
Description: Antibody raised against LRRTM2

anti- LRRTM4 antibody

FNab04865 100µg
EUR 658.5
Description: Antibody raised against LRRTM4

anti- LRSAM1 antibody

FNab04866 100µg
EUR 658.5
Description: Antibody raised against LRSAM1

anti- LRWD1 antibody

FNab04867 100µg
EUR 702
Description: Antibody raised against LRWD1

anti- LSAMP antibody

FNab04868 100µg
EUR 658.5
Description: Antibody raised against LSAMP

anti- LSG1 antibody

FNab04869 100µg
EUR 658.5
Description: Antibody raised against LSG1

anti- LSM1 antibody

FNab04870 100µg
EUR 606.3
Description: Antibody raised against LSM1

anti- LSM10 antibody

FNab04871 100µg
EUR 658.5
Description: Antibody raised against LSM10

anti- LSM11 antibody

FNab04872 100µg
EUR 702
Description: Antibody raised against LSM11

anti- LSM14A antibody

FNab04873 100µg
EUR 658.5
Description: Antibody raised against LSM14A

anti- LSM2 antibody

FNab04874 100µg
EUR 606.3
Description: Antibody raised against LSM2

anti- LSM4 antibody

FNab04875 100µg
EUR 658.5
Description: Antibody raised against LSM4

anti- LSM5 antibody

FNab04876 100µg
EUR 702
Description: Antibody raised against LSM5

anti- LSM7 antibody

FNab04877 100µg
EUR 606.3
Description: Antibody raised against LSM7

anti- LSM8 antibody

FNab04878 100µg
EUR 606.3
Description: Antibody raised against LSM8

anti- LSP1 antibody

FNab04879 100µg
EUR 702
Description: Antibody raised against LSP1

anti- LSR antibody

FNab04880 100µg
EUR 606.3
Description: Antibody raised against LSR

anti- LSS antibody

FNab04881 100µg
EUR 606.3
Description: Antibody raised against LSS

anti- LSS antibody

FNab04882 100µg
EUR 606.3
Description: Antibody raised against LSS

anti- LTA4H antibody

FNab04883 100µg
EUR 606.3
Description: Antibody raised against LTA4H

anti- LTB4R antibody

FNab04884 100µg
EUR 702
Description: Antibody raised against LTB4R

anti- LTBP1 antibody

FNab04885 100µg
EUR 606.3
Description: Antibody raised against LTBP1

anti- LTBP2 antibody

FNab04886 100µg
EUR 606.3
Description: Antibody raised against LTBP2

anti- LTBR antibody

FNab04887 100µg
EUR 658.5
Description: Antibody raised against LTBR

anti- LUC7L antibody

FNab04888 100µg
EUR 606.3
Description: Antibody raised against LUC7L

anti- LUC7L2 antibody

FNab04889 100µg
EUR 702
Description: Antibody raised against LUC7L2

anti- Lumican antibody

FNab04890 100µg
EUR 606.3
Description: Antibody raised against Lumican


Separase, a sister chromatid cohesion enzyme-finish, is an oncogene and is expressed in many human cancers. Sepin-1 (2,2-dimethyl-5-nitro-2H-benzimidazole-1,3-dioxide) is a potent inhibitor Separase which inhibit cancer cell growth, cell migration and wound healing, indicating that Sepin-1 has a great potential with a target separase-overexpressing tumors.

Karina

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